This congenic encodes the BALB/c variant of the H60a minor histocompatibility antigen. The strain C57BL/6 is H60ab.
The H60ac allele from BALB/cBy was backcrosssed onto C57BL/6J for at least 16 backcrosses. When maintained in the laboratory of Dr. Derry Roopenian The SSLP marker D10Dcr2, which is polymorphic between C57BL/6J and BALB, was used as a genotyping marker closely linked to this allele.
|Allele Name||c variant|
|Allele Type||Not Applicable|
|Gene Symbol and Name||H60a, histocompatibility 60a|
|Strain of Origin||BALB/c|
|Molecular Note||There are three markers whose symbols begin "H60" - H60a, H60b and H60c. All three reside on Chr 10. The original is now H60a; the others were reported in J Immunol in February, 2008 (J:131505). H60ac encodes the BALB/c variant of the H60a minor histocompatibility antigen (J:49824).|