Mouse Strain Datasheet - 003897
Mouse Strain Datasheet - 003897
These Abca1 knock-out mice exhibit reduced cholesterol and plasma phospholipid levels along with a lack of high density lipoproteins (HDL) . Macrophage ability to engulf apoptotic cells is impaired and lipid rich macrophages and type II pneumocytes accumulate in the lungs.
John D. McNeish, Pfizer Central Research
| Genetic Background | Generation |
|---|---|
|
|
| Allele Type | Gene Symbol | Gene Name |
|---|---|---|
| Targeted (Null/Knockout) | Abca1 | ATP-binding cassette, sub-family A (ABC1), member 1 |
| Service | Genotype | Price |
|---|---|---|
| Heterozygous or Wild-type for Abca1<tm1Jdm> |
We will fulfill your order by providing at least two carriers for each strain ordered. The total number, sex, and genotypes provided will vary, although typically 8 or more animals are provided. Please check genotypes which will be recovered. While the genotypes of all animals produced will be communicated to you prior to scheduling shipment, the genotypes of animals provided may not reflect the mating scheme and genotypes described in the strain description. Animals are typically ready to ship in 11-14 weeks. If a second recovery is required to produce the minimum number of animals, then delivery time would increase to approximately 25 weeks. If we fail to produce animals of the correct genotype, you will not be charged. We cannot guarantee the reproductive success of mice shipped to your facility. If the mice are lost after the first three days (post-arrival) or do not produce progeny at your facility, a new order and fee will be necessary.
Cryorecovery to establish a Dedicated Supply for greater quantities of mice. Mice recovered can be used to establish a dedicated colony to contractually supply you mice according to your requirements. Price by quotation.
| Frozen Mouse Embryo | DBA/1-Abca1<tm1Jdm>/J Frozen Embryos | $2595.00 |
| Frozen Mouse Embryo | DBA/1-Abca1<tm1Jdm>/J Frozen Embryos | $2595.00 |
| Frozen Mouse Embryo | DBA/1-Abca1<tm1Jdm>/J Frozen Embryos | $3373.50 |
| Frozen Mouse Embryo | DBA/1-Abca1<tm1Jdm>/J Frozen Embryos | $3373.50 |
