NOD.129P2(B6)-Sell^tm1Tft/1LtJ

Stock number: 003860
Product name: NOD.CD62L
Research areas: Immunology, Inflammation and Autoimmunity Research, Internal/Organ Research

Detailed description

Lymphocytes from these Sell knock-out mice exhibit severe reduction in the number of lymphocytes localized to peripheral lymph nodes and are significantly impaired in delayed-type hypersensitivity reactions

Allele

Symbol: Sell^tm1Tft
Name: targeted mutation 1, Thomas F Tedder
MGI accession ID: MGI:1927795
Generation method: Targeted
Attributes: Null/Knockout
Marker symbol: Sell
Marker name: selectin, lymphocyte
Chromosome: 1
Strain of origin: 129P2/OlaHsd
Molecular note: A neomycin resistance gene replaced the majority of the exon encoding the L-selectin domain.