NOD.B6(PL)-(D3Mit213-D3Mit124)/Lt

Stock number: 003850

Allele

Symbol: Idd10^C57BL/6J
Name: C57BL/6J
MGI accession ID: MGI:3038835
Generation method: QTL
Marker symbol: Idd10
Marker name: insulin dependent diabetes susceptibility 10
Chromosome: 3
Strain of origin: C57BL/6J
Molecular note: This allele confers resistance to insulin dependent diabetes compared to NOD.
General note: Idd10 and Idd18 interact to promote disease resistance. Homozygosity for C57BL/6-derived alleles at both Idd10 and Idd18 confers significantly increased resistance to type 1 diabetes.

Idd10 and Idd17 interact to promote disease resistance. Homozygosity for C57BL/6-derived alleles at both Idd10 and Idd17 confers significantly increased resistance to type 1 diabetes.

Idd10 and Idd3 interact to promote disease resistance. Homozygosity for C57BL/6-derived alleles at both Idd10 and Idd3 confers significantly increased resistance to type 1 diabetes.

Allele

MGI accession ID: MGI:92488
Marker symbol: D3Mit213
Marker name: DNA segment, Chr 3, Massachusetts Institute of Technology 213
Chromosome: 3

Allele

MGI accession ID: MGI:92391
Marker symbol: D3Mit124
Marker name: DNA segment, Chr 3, Massachusetts Institute of Technology 124
Chromosome: 3