This recessive phenotypic marker arose spontaneously in the NOD/ShiLtJ inbred background. Homozygotes have normal lenses at two weeks of age but cataracts in both eyes by two months of age. Suture lines are visible and the lens fibers show, but no vacuolization has been found. ERG readings are normal both before and after cataract development. This mutation has been mapped to Chromosome 2, but the underlying mutation remains to be defined.

Jackson cataract homozygotes have normal lenses at two weeks of age but develop cataracts in both eyes by two months of age. This mutation has been mapped to Chromosome 2, but the underlying mutation remains to be defined.

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