Homozygotes are embryonic lethal. The Lexicon Genetics Omnibank Sequence Tag (OST) number associated with this strain is OST75692. More sequence information is available at their website.
Importation of this model was supported by the Merck Genome Research Institute (MGRI). The MGRI strains have not been characterized in any great detail. In some instances, rudimentary expression information is available. We plan to update strain information as published results become available.
The Vmn2r10 gene was disrupted in Lex-1 embryonic stem cells (derived from 129S5/SvEvBrd). Selected cells were injected into C57BL/6-Tyrc-Brd/c-Brd blastocysts.
|Allele Name||gene trap OST75692, Lexicon Genetics|
|Allele Type||Gene trapped (Reporter, Null/Knockout)|
|Gene Symbol and Name||Gt(OST75692)Lex, gene trap insertion OST75692, Lexicon Genetics|
|Strain of Origin||129S5/SvEvBrd|
|Molecular Note||The gene was disrupted by the insertion of the gene trap vector. Further molecular details are not available.|
|Mutations Made By|| |
Ramiro Ramirez-Solls, Lexicon Genetics Incorporated