This transgenic strain is used to trace glial cell lineage from the early stages throughout their development while simultaneously selecting for oligodendrocytes and Schwann cells. The transgenic mice contain a bacterial b-galactosidase and neomycin phosphotransferase fusion protein (bgeo) under the control of murine 2'3'-cyclic nucleotide 3'-phosphodiesterase (muCNP) promoters I and II. No overt phenotype is observed.

These muCNP-&Beta;geo transgenic mice express a beta geo fusion protein under the control of murine cyclic nucleotide phosphodiesterase 1 (<i>Cnp1</i>) promoters I and II.


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