B6;C3H-Tg(CNP-GEO)1Ldh/J

Stock number: 003471
Product name: muCNP-Βgeo
Research areas: Neurobiology Research, Research Tools

Description

These muCNP-Βgeo transgenic mice express a beta geo fusion protein under the control of murine cyclic nucleotide phosphodiesterase 1 (Cnp1) promoters I and II.

Detailed description

This transgenic strain is used to trace glial cell lineage from the early stages throughout their development while simultaneously selecting for oligodendrocytes and Schwann cells. The transgenic mice contain a bacterial b-galactosidase and neomycin phosphotransferase fusion protein (bgeo) under the control of murine 2'3'-cyclic nucleotide 3'-phosphodiesterase (muCNP) promoters I and II. No overt phenotype is observed.

Allele

Symbol: Tg(CNP-GEO)1Ldh
Name: transgene insertion 1, Lynn D Hudson
MGI accession ID: MGI:3056373
Generation method: Transgenic
Attributes: Reporter
Synonyms: CNP-GEO
Marker symbol: Tg(CNP-GEO)1Ldh
Marker name: transgene insertion 1, Lynn D Hudson
Marker synonyms: CNP-GEO
Chromosome: UN
Strain of origin: (C57BL/6J x C3H)F2
Expressed genes: Bgeo,fusion of beta-galactosidase and neomycin phosphotransferase genes,E. coli
Site of expression: Glial cell lineage from the early stages throughout their development.
Molecular note: The transgene expresses a bacterial beta-galactosidase and neomycin phosphotransferase fusion protein (bgeo) under the control of murine cyclic nucleotide phosphodiesterase 1 (Cnp1) promoters I and II.
General note: Transgenic mice exhibit no overt phenotype.