Mice carrying the human apolipoprotein CI transgene are viable and fertile. They show elevated plasma triglycerides in both fasted and fed states. They also have elevated plasma cholesterol, increased VLDL, increased LDL, increased plasma APOB, and slowed clearance of both VLDL triglycerides and postlipolysis lipoprotein remnants. This strain serves as a model of decreased clearance of postprandial triglycerides and lipoprotein remnants.

These HuCI Tg mice express a transgene containing the human APOC1 gene.




Typically mice are recovered in 12-16 weeks. Contact Customer Service to place an order or for more information.

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