129P3/JEmsJ

Stock number: 002357
Research areas: Cancer Research, Cardiovascular Research, Neurobiology Research, Reproductive Biology Research, Research Tools, Sensorineural Research

Allele

Symbol: Disc1^del
Name: deletion
MGI accession ID: MGI:3623217
Generation method: Spontaneous
Synonyms: Disc1^129S6; Disc1^delta6
Marker symbol: Disc1
Marker name: disrupted in schizophrenia 1
Marker synonyms: C1orf136; SCZD9
Chromosome: 8
Strain of origin: various
Molecular note: A 25 bp deletion in exon 6 causes a frame shift in the reading frame, resulting in 13 novel amino acids and a premature stop codon in exon 7.
General note: This deletion appears in multiple strains of the 129 superfamily, 101/RI, BTBR T⁺ tf/J, LP/J, FVB/NJ, SJL/J, SWR/J and DDY/JclSidSeyFrkJ (J:111837, J:195189).