NXSMC/Ei-Dct^slt-2J/J

Stock number: 002345
Product name: slaty 2 Jackso
Research areas: Dermatology Research

Detailed description

These mice carry the spontaneous Dct^slt-2J mutation which has a similar phenotype to the original slaty (slt) mutation which has a 3- to 10-fold reduction in enzyme activity and produces a dark gray/brown eumelanin.

Allele

Symbol: Dct^slt-2J
Name: slaty 2 Jackson
MGI accession ID: MGI:1856380
Generation method: Spontaneous
Marker symbol: Dct
Marker name: dopachrome tautomerase
Marker synonyms: OCA8; TRP2; TRP-2; tyrosinase-related protein-2; TYRP2; Tyrp-2
Chromosome: 14
Strain of origin: NXSMC/EiJ
Molecular note: Sequence analysis of DNA from this allele revealed a C to T substitution at base 1764.