This deletion is a dominant mutation causing white spotting on the feet, tail, belly, and occasionally elsewhere. Homozygosity is embryonic lethal. On the C57BL/6 background approximately 60% of heterozygous females have a closed vagina. The ovaries from these heterozygotes are normal and fine for transplantation. On the C57BL/6 background in the presence of the YAKR/J Chromosome (available from Stock No. <a href="https://www.jax.org/strain/007250">007250</a>), KitW-19H heterozygosity results in sex reversed XY females.

These mice carry a spontaneous, dominant mutation at the Kit locus characterized by white spotting on the feet, tail, and belly in heterozygotes and embryonic lethality in homozygotes.

Typically mice are recovered in 12-16 weeks. Contact Customer Service to place an order or for more information.

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