B6.Cg-Is(HSR;1)1Lub/J

Stock number: 001914
Research areas: Research Tools

Description

These mice carry an extra chromosomal segment, seen in wild mouse populations, in chromosome 1, and referred to as a homogeneously staining region (HSR).

Detailed description

Is(HSR;1)1Lub does not appear to impact viability or impart any other outward phenotype.

Development

Is(HSR;1)1Lub was backcrossed from the, now extinct, RBA1/Dn mutant subline of RBA/DnJ (see Mouse News Letter 1986, v75 p34) onto C57BL/6J for 10 generations before embryos were generated for cryopreservation from homozygous males bred with C57BL/6J females. Cryorecovered pups will be hemizygotes at backcross generation N11.

Allele

MGI accession ID: MGI:103610
Marker symbol: Is(HSR;1)1Lub
Marker name: insertion, homogeneous staining region, Chr 1, Lubeck 1
Marker synonyms: Is1Lub
Chromosome: 1