The BALB/cGaJ inbred strain has been reported by donating investigator Allen Gates to have high fertility relative to many inbred strains, including BALB/cByJ, delayed reproductive senility to at least 12 months of age, excellent monoclonal antibody production, and delay of male aggression to approximately 5 months of age.
Allen Gates, University of Rochester
The BALB/cGaJ inbred strain has been reported by donating investigator Allen Gates to have high fertility relative to many inbred strains, including BALB/cByJ, delayed reproductive senility to at least 12 months of age, excellent monoclonal antibody production, and delay of male aggression to approximately 5 months of age.
Inbreeding of BALB/c began in 1922 by MacDowell and mice were transferred to Snell in 1932 when the line was at generation F26, then to Heston and to Andervont in 1935 when the strain was at approximately F34 then to The Cancer Research Genetics Laboratory of The University of California at Berkley (Crgl) in 1950 when the strain was at generation F60, then to Allen Gates (Ga) in 1960 when the strain was at generation F72, then to Hugh McDevitt (Mcd) in 1970 when the strain was at generation F72+20, then back to Allen Gates in 1971 when the strain was at generation F72+24. In 1986 this strain reached generation F72+57 and in 1989 mice were sent from Allen Gates to The Jackson Laboratory at generation F72+66 (cumulative generation F138). These were re-derived and expanded by sibling breeding and cryopreserved.
Currently there are no related genes or alleles for this strain.
When using the BALB/cGaJ mouse strain in a publication, please include JAX stock #001905 in your Materials and Methods section.
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The Jackson Laboratory has rigorous genetic quality control and mutant gene genotyping programs to ensure the genetic background of JAX® Mice strains as well as the genotypes of strains with identified molecular mutations. JAX® Mice strains are only made available to researchers after meeting our standards. However, the phenotype of each strain may not be fully characterized and/or captured in the strain data sheets. Therefore, we cannot guarantee a strain's phenotype will meet all expectations. To ensure that JAX® Mice will meet the needs of individual research projects or when requesting a strain that is new to your research, we suggest ordering and performing tests on a small number of mice to determine suitability for your particular project. We do not guarantee breeding performance and therefore suggest that investigators order more than one breeding pair to avoid delays in their research.
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