These mice carry the spontaneous (us mutation, and homozygotes can be distinguished at birth by small size and a kinky tail. Skeletal abnormalities also include split arches and fusions in cervical vertebrae, fusions in thoracic and lumbar vertebrae and unilateral and bilateral fusions of one or more ribs. Delayed growth, sterility, kidney abnormalities, and abnormalities of the urogenital system also occur. Affected mice appear to have a thinner hair coat with fewer zigzag hairs and narrower awls than normal and slightly abnormal behavior.
|Allele Name||urogenital syndrome|
|Gene Symbol and Name||us, urogenital syndrome|
|Strain of Origin||STOCK Tgm3we Atrnmg a|
|General Note||The mutation has been proposed as a model for human nail-patella-syndrome (OMIM 161200; J:14466).|