LT.MA-Glo1^b H2^d/J

Stock number: 001382
Research areas: Immunology, Inflammation and Autoimmunity Research

Detailed description

These congenic mice carry the Glo allele from the MA/MyJ strain and the H2 haplotype from the LT/SvEi background strain.

Development

The b allele of Glo1 was backcrossed from MA/MyJ onto LT/SvEi for 10 generations before intercrossing. In 1990 LT/SvEi females were bred with N10F31 homozygous male to generate embryos for cryopreservation. (Eppig and Eicher, 1983.)

Allele

Symbol: H2^d
Name: d variant
MGI accession ID: MGI:3579320
Generation method: Spontaneous
Marker symbol: H2
Marker name: histocompatibility-2, MHC
Marker synonyms: H-2; MHC-II
Chromosome: 17
Strain of origin: various
General note: The d variant has been observed in the following strains: DBA/2, DBA/2J BALB/c, BALB/cByJ, BALB/cJ, C57BLKS, NZB.

Allele

MGI accession ID: MGI:95742
Marker symbol: Glo1
Marker name: glyoxalase 1
Marker synonyms: 0610009E22Rik; 1110008E19Rik; 2510049H23Rik; Glo-1; Glo-1r; Glo1-r; Glo-1s; Glo1-s; GLOD1; GLYI; HEL-S-74; Qglo
Chromosome: 17