NOD/ShiLt

Stock number: 001289

Allele

Symbol: Il2^m1
Name: mutation 1
MGI accession ID: MGI:4352594
Generation method: Spontaneous
Marker symbol: Il2
Marker name: interleukin 2
Marker synonyms: IL-2; lymphokine; TCGF
Chromosome: 3
Strain of origin: multiple strains
Molecular note: This hypoactive polymorphism, found in MRL/MpJ, SJL/J, and NOD/ShiLtJ inbred strains, includes a smaller polyglutamine tract predicted to shorten the first alpha helix, which forms part of the IL2 receptor binding site.

Allele

Symbol: Del(1)2Lt
Name: deletion, Chr 1, Edward H Leiter 2
MGI accession ID: MGI:6150933
Generation method: Spontaneous
Attributes: Not Applicable
Marker symbol: Del(1)2Lt
Marker name: deletion, Chr 1, Edward H Leiter 2
Marker synonyms: Del2Lt
Chromosome: 1
Strain of origin: NOD/ShiLtJ
Molecular note: This spontaneous 25,703 bp deletion in Chromosome 1 spans from 39,088,990 bp to 39,114,692 bp (GRCm38).

Allele

Symbol: Del(3)3Lt
Name: deletion, Chr 3, Edward H Leiter 3
MGI accession ID: MGI:6150936
Generation method: Spontaneous
Attributes: Not Applicable
Marker symbol: Del(3)3Lt
Marker name: deletion, Chr 3, Edward H Leiter 3
Marker synonyms: Del3Lt
Chromosome: 3
Strain of origin: NOD/ShiLtJ
Molecular note: This spontaneous 4,289 bp deletion in Chromosome 3 spans from 33,746,227 bp to 33,750,515 bp (GRCm38).