Allele Name | mutation 1 |
---|---|
Allele Type | Spontaneous |
Allele Synonym(s) | |
Gene Symbol and Name | Il2, interleukin 2 |
Gene Synonym(s) | |
Strain of Origin | multiple strains |
Chromosome | 3 |
Molecular Note | This hypoactive polymorphism, found in MRL/MpJ, SJL/J, and NOD/ShiLtJ inbred strains, includes a smaller polyglutamine tract predicted to shorten the first alpha helix, which forms part of the IL2 receptor binding site. |
Allele Name | deletion, Chr 1, Edward H Leiter 2 |
---|---|
Allele Type | Spontaneous (Not Applicable) |
Allele Synonym(s) | |
Gene Symbol and Name | Del(1)2Lt, deletion, Chr 1, Edward H Leiter 2 |
Gene Synonym(s) | |
Strain of Origin | NOD/ShiLtJ |
Chromosome | 1 |
Molecular Note | This spontaneous 25,703 bp deletion in Chromosome 1 spans from 39,088,990 bp to 39,114,692 bp (GRCm38). |
Allele Name | deletion, Chr 3, Edward H Leiter 3 |
---|---|
Allele Type | Spontaneous (Not Applicable) |
Allele Synonym(s) | |
Gene Symbol and Name | Del(3)3Lt, deletion, Chr 3, Edward H Leiter 3 |
Gene Synonym(s) | |
Strain of Origin | NOD/ShiLtJ |
Chromosome | 3 |
Molecular Note | This spontaneous 4,289 bp deletion in Chromosome 3 spans from 33,746,227 bp to 33,750,515 bp (GRCm38). |
When using the NOD/ShiLt mouse strain in a publication, please include JAX stock #001289 in your Materials and Methods section.
Facility Barrier Level Descriptions
Service/Product | Description | Price |
---|---|---|
Inbred, 1 pair minimum will be supplied |
Terms are granted by individual review and stated on the customer invoice(s) and account statement. These transactions are payable in U.S. currency within the granted terms. Payment for services, products, shipping containers, and shipping costs that are rendered are expected within the payment terms indicated on the invoice or stated by contract. Invoices and account balances in arrears of stated terms may result in The Jackson Laboratory pursuing collection activities including but not limited to outside agencies and court filings.
The Jackson Laboratory has rigorous genetic quality control and mutant gene genotyping programs to ensure the genetic background of JAX® Mice strains as well as the genotypes of strains with identified molecular mutations. JAX® Mice strains are only made available to researchers after meeting our standards. However, the phenotype of each strain may not be fully characterized and/or captured in the strain data sheets. Therefore, we cannot guarantee a strain's phenotype will meet all expectations. To ensure that JAX® Mice will meet the needs of individual research projects or when requesting a strain that is new to your research, we suggest ordering and performing tests on a small number of mice to determine suitability for your particular project. We do not guarantee breeding performance and therefore suggest that investigators order more than one breeding pair to avoid delays in their research.
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