Overview

Also Known As:BALB Bailey Jackson, BALB/c Bailey Jackson, CByJ

Mice of this substrain of BALB/c, among other differences, have better reproductive performance and less aggression than mice of the BALB/cJ substrain (Stock No. 000651).

Genetic overview

Genetic Background	Generation
	Contact Technical Support (2018-07-27 00:00:00)

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Research Applications

Neurobiology Research
Sensorineural Research
Research Tools
Immunology, Inflammation and Autoimmunity Research
Cancer Research
Cardiovascular Research

View All Research Applications

Base Price

Starting at:

$34.16 Domestic price for female 3-week

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Details

Important Note

This strain is homozygous for Cdh23^ahl, the age related hearing loss 1 mutation, which on this background results in progressive hearing loss with onset after 10 months of age.

Detailed Description

BALB/c mice are particularly well known for the production of plasmacytoma on injection with mineral oil, forming the basis for the production of monoclonal antibodies. Although not all BALB/c substrains have been examined for plasmacytoma induction, substrains derived from the Andervont (An) lineage (which includes BALB/cByJ) typically are susceptible, while those descended from BALB/cJ are resistant. Mammary tumor incidence is normally low, but infection with mammary tumor virus by fostering to MMTV⁺ C3H mice dramatically increases tumor number and age of onset. BALB/c mice develop other cancers later in life, including reticular neoplasm, primary lung tumors, and renal tumors. Rare spontaneous myoepitheliomas arising from myoepithelial cells of various exocrine glands have been observed in both BALB/cJ and BALB/cByJ substrains. A deficiency of Acads (acyl-Coenzyme A dehydrogenase, short chain) leads to severe organic aciduria. BALB/cByJ develop a fatty liver upon fasting or dietary fat challenge and become hypoglycemic after an 18-hour fast. BALB/cByJ mice have the advantage of better reproductive performance and less aggression than mice of the BALB/cJ substrain.

BALB/c mice are predisposed to dystrophic cardiac calcinosis (mineralization of cardiac tissues). Using BALB/cByJ and BALB/cJ mice obtained from The Jackson Laboratory, a study by the laboratory of Dr. Steven Taffet reports that BALB/cByJ mice exhibited more frequent and severe calcium deposition (44/49; 90% at 5 weeks of age) than did BALB/cJ (1/6; 17% at 5 weeks of age) or other BALB/c substrains [Glass et al. 2013 Comp Med 63: 29 (PMID:23561935)].

Development

This is a substrain of BALB (Bagg’s albino) derived initially from the BALB strain maintained by MacDowell at Cold Spring Harbor, eventually sent to Andervont as BALB/cAn and to NIH where D.W. Bailey obtained the substrain and maintained it through locations at the University of California Medical School at San Francisco and ultimately at The Jackson Laboratory. In 1975 at generation F136 BALB/cBy (Stock No. 000650) mice were sent to JAX production facility upon hysterectomy derivation and became the BALB/cByJ substrain.

The Andervont/Bailey lineage and the lineage giving rise to BALB/cJ were separated from the BALB/c line maintained by Snell at The Jackson Laboratory during the period of 1937 to 1939 around generation F36.

Selected References

Bentvelzen P; Daams JH; Hageman P; Calafat J. 1970. Genetic transmission of viruses that incite mammary tumor in mice. Proc Natl Acad Sci U S A 67(1):377-84PubMed: 4318784 MGI: J:24803
Champy MF; Selloum M; Zeitler V; Caradec C; Jung B; Rousseau S; Pouilly L; Sorg T; Auwerx J. 2008. Genetic background determines metabolic phenotypes in the mouse. Mamm Genome 19(5):318-31PubMed: 18392653 MGI: J:137669
Ebbesen P. 1971. Reticulosarcoma and amyloid development in BALB/c mice inoculated with syngeneic cells from young and old donors. J Natl Cancer Inst 47(6):1241-5PubMed: 4941118 MGI: J:24297
Heston WE; Vlahakis G. 1971. Mammary tumors, plaques, and hyperplastic alveolar nodules in various combinations of mouse inbred strains and the different lines of the mammary tumor virus. Int J Cancer 7(1):141-8PubMed: 4322934 MGI: J:24674
Hinsdale ME; Kelly CL; Wood PA. 1993. Null allele at Bcd-1 locus in BALB/cByJ mice is due to a deletion in the short-chain acyl-CoA dehydrogenase gene and results in missplicing of mRNA. Genomics 16(3):605-11PubMed: 8325633 MGI: J:12776
Petkov PM; Cassell MA; Sargent EE; Donnelly CJ; Robinson P; Crew V; Asquith S; Haar RV; Wiles MV. 2004. Development of a SNP genotyping panel for genetic monitoring of the laboratory mouse. Genomics 83(5):902-11PubMed: 15081119 MGI: J:89298
Roderick TH; Langley SH; Leiter EH. 1985. Some unusual genetic characteristics of BALB/c and evidence for genetic variation among BALB/c substrains. Curr Top Microbiol Immunol 122:9-18PubMed: 3899524 MGI: J:24307
Smith Richards BK; Belton BN; York B; Volaufova J. 2004. Mice bearing Acads mutation display altered postingestive but not 5-s orosensory response to dietary fat. Am J Physiol Regul Integr Comp Physiol 286(2):R311-9PubMed: 14592933 MGI: J:87779
Sundberg JP; Hanson CA; Roop DR; Brown KS; Bedigian HG. 1991. Myoepitheliomas in inbred laboratory mice. Vet Pathol 28(4):313-23PubMed: 1719689 MGI: J:22767
Wood PA; Amendt BA; Rhead WJ; Millington DS; Inoue F; Armstrong D. 1989. Short-chain acyl-coenzyme A dehydrogenase deficiency in mice. Pediatr Res 25(1):38-43PubMed: 2919115 MGI: J:14707
Wood PA; Hinsdale ME; Kelly CL. 1993. Molecular detection of the Bcd-1 null allele in BALB/cByJ mice by polymerase chain reaction: a simple assay for genetic monitoring Mouse Genome 91(2):342-44MGI: J:12812

View All References

Genetics

Hld

Allele Symbol: Hld

Allele Name	hippocampal lamination defect
Allele Type	Spontaneous
Allele Synonym(s)
Gene Symbol and Name	Hld, hippocampal lamination defect
Gene Synonym(s)
Strain of Origin	BALB/cJ
Chromosome	UN

Ahr^b-2

Allele Symbol: Ahr^b-2

Allele Name	b-2 variant
Allele Type	Not Applicable
Allele Synonym(s)	Ah^b-2; Ah^h
Gene Symbol and Name	Ahr, aryl-hydrocarbon receptor
Gene Synonym(s)
Strain of Origin	BALB/cBy
Chromosome	12
General Note	C57BL/6 carries the responsive Ahr^b allele; DBA/2 carries nonresponsive Ahr^d. Heterozygotes (Ahr^b/Ahr^d) are responsive (J:5282). Later work identified a second (J:8895) and later a third (J:22144) allele conferring response. Thus the allele in C57, C58, and MA/My strains is now Ahr^b-1; Ahr^b-2 is carried by BALB/cBy, A, and C3H; and Ahr^b-3 by Mus spretus, M. caroli, and MOLF/Ei. The nonresponsive strains AKR, DBA/2, and 129 carry Ahrd (J:22144). Nucleotide and amino acid sequence differences between Ahr^b-1 and Ahr^d have been determined (J:17460). Strain of origin - this allele was found in BALB/cByJ, A/J, C3H/HeJ, CBA strains
Molecular Note	This allele encodes a high affinity, heat labile, 104 kDa receptor containing 848 amino acids. Sequencing studies of cDNA from C57BL/6J congenic mice homozygous for this allele identified nucleotide substitutions in the ORF that would cause 5 amino acid differences between the C57BL/6J and BALB/cBy peptides, and 2 amino acid differences between the BALB/cBy and DBA/2J peptides. A T to C transition in exon 11 replaces the opal termination codon in the C57BL/6J allele with an arginine codon in the BALB/cBy allele. This change would extend translation of the BALB/cBy mRNA by 43 amino acids, accounting for the larger size of the peptide produced by this allele (104 kDa, vs 95 kDa for the C57BL/6J allele).

Cdh23^ahl

Allele Symbol: Cdh23^ahl

Allele Name	age related hearing loss 1
Allele Type	Spontaneous
Allele Synonym(s)	Cdh23^753A; mdfw
Gene Symbol and Name	Cdh23, cadherin 23 (otocadherin)
Gene Synonym(s)
Strain of Origin	multiple strains
Chromosome	10
Molecular Note	Genetic complementation tests have shown allelism between the mdfw (modifier of deaf waddler) locus and the ahl locus. Further analysis has shown this is caused by a G to A transition at coding nucleotide position 753 of Cdh23 (SNP rs257098870). This hypomorphic allele changes splice donor site G-GT to A-GT, causing frame skipping of exon 7. This is predicted to delete part of the 2nd and 3rd ectodomains and cause reduced message stability. Twenty-seven strains classified with ahl and carrying the 753A allele include: CD-1, RBF/DnJ, PL/J, AKR/J, RF/J, BALB/cBy, A/WySnJ, P/J, SENCARA/PtJ, DBA/1J, ALS/LtJ, C58/J, C57BLKS/J, 129P1/ReJ, C57BR/cd, SKH2/J, BUB/Bn, MA/MyJ, LP/J, 129X1/SvJ, NOR/LtJ, A/J, C57BL/6, NOD/LtJ, DBA/2J, ALR/LtJ, C57L/J. Strains classified with ahl that DO NOT carry this mutation include: 129S1/SvImJ, C3H/HeSnJ, I/LnJ, YBR/Ei, MRL/MpJ.

Acads^del-J

Allele Symbol: Acads^del-J

Allele Name	deletion, Jackson
Allele Type	Spontaneous (Null/Knockout)
Allele Synonym(s)	Bcd-1^c; Scad
Gene Symbol and Name	Acads, acyl-Coenzyme A dehydrogenase, short chain
Gene Synonym(s)
Strain of Origin	BALB/cByJ
Chromosome	5
Molecular Note	A 278bp deletion occurs which starts in intron "A" and includes exon "B" and the first 78bp of exon "C". As a result of this deletion, mRNA transcription is reduced to about 35% of normal and includes two forms, a longer normal length transcript and a shorter misspliced form. If these mRNAs were translated they both would result in truncated products. Protein product is undetectable immunologically and there is a total absence of enzyme activity.

If1^l

Allele Symbol: If1^l

Allele Name	low response
Allele Type	Spontaneous (Hypomorph)
Allele Synonym(s)
Gene Symbol and Name	If1, NDV-induced circulating interferon
Gene Synonym(s)
Strain of Origin	BALB/c
Chromosome	3
Molecular Note	This phenotypic variation causing decreased interferon production in response to particular stimuli has been mapped to distal Chromosome 3

B2m^a

Allele Symbol: B2m^a

Allele Name	a variant
Allele Type	Spontaneous (Not Applicable)
Allele Synonym(s)
Gene Symbol and Name	B2m, beta-2 microglobulin
Gene Synonym(s)
Strain of Origin	multiple strains
Chromosome	2
Molecular Note	The a variant is slightly slower running on SDS PAGE and was found to have an aspartic acid at amino acid position 85. This allele is found in A, BALB/c, LP and most other strains.

Mdmg1

Marker Symbol: Mdmg1

Marker Synonym(s)
Chromosome(s)	17

Disease/Phenotype

Disease Terms

Model with phenotypic similarity to human disease where etiologies involve orthologs. Human genes are associated with this disease. Orthologs of those genes appear in the mouse genotype(s).

short chain acyl-CoA dehydrogenase deficiency

Research Areas By Phenotype

This mouse can be used to support research in many areas including:

Genotype: Cdh23^ahl related

Neurobiology Research
- Hearing Defects
  - Age related hearing loss
Sensorineural Research
- Hearing Defects
  - Age related hearing loss

Neurobiology Research
- Neurodevelopmental Defects
  - callosal agenesis, incomplete penetrance
- Hearing Defects
  - Age related hearing loss
Research Tools
- Cancer Research
  - monoclonal antibodies, myeloma and hybridoma production
- Cardiovascular Research
- General Purpose
- Immunology, Inflammation and Autoimmunity Research
  - background strain for histocompatibility congenics
Immunology, Inflammation and Autoimmunity Research
- Autoimmunity
  - experimental allergic encephalomyelitis (EAE)
Cancer Research
- Increased Tumor Incidence
  - Mammary Gland Tumors
  - Mammary Gland Tumors: late onset
Cardiovascular Research
- Heart Abnormalities
Sensorineural Research
- Hearing Defects
  - Age related hearing loss

Mammalian Phenotype Terms by Genotype

The following phenotype relates to a compound genotype created using this strain

Genotype: Acads^del-J/Acads^del-J
involves: BALB/cByJ

homeostasis/metabolism phenotype

hypoglycemia
- hypoglycemia develops after 18 hours of fasting with mean serum glucose measuring less than half of control values

organic aciduria
- upon dosing with carnitine, mice excrete large amounts of butyryl-carnitine in the urine
- organic aciduria at 7-14 weeks of age, caused by relatively large amounts of n-butyrylglycine and ethylmalonate in the urine
- markedly increased urinary concentrations of ethylmalonic and methylsuccinic acids, and N-butyrylglycine in nonfasting and fasting mice, and remained elevated with or without medium chain triglyceride challenge
- ethylmalonate, methylsuccinate, and butyrylglycine urinary excretion is higher than in controls

increased circulating HDL cholesterol level
- HDL levels were significantly increased in mutant mice for both males and females fed either a regular chow or a high-fat diet

ethylmalonic aciduria
- relatively large amounts of ethylmalonate in the urine at 7-14 weeks of age
- ethylmalonate urinary excretion is higher than in controls

abnormal fatty acid oxidation
- block in short-chain fatty acid oxidation shown by reduced butyryl-CoA dehydrogenation in liver mitochondria

decreased circulating glycine level
- serum glycine concentrations are markedly lower than in controls

abnormal adaptive thermogenesis
- body temperature in most BALB/cByJ mice dropped 10 degrees C in less than 4 h at 4 degrees C, with none able to maintain body temperature for longer than 8 h in the cold

decreased circulating carnitine level
- slightly lower plasma carnitine level

liver/biliary system phenotype

hepatic steatosis
- fat deposits accumulate in the liver after 18 hours of fasting or with dietary fat challenge

muscle phenotype

abnormal skeletal muscle morphology
- wehn dosed with carnitine, mutant muscle exhibits a 9-fold increase in butyryl-carnitine concentration compared to controls

nervous system phenotype

decreased circulating glycine level
- serum glycine concentrations are markedly lower than in controls

behavior/neurological phenotype

abnormal liquid preference
- did not develop a preference for drinking water containing a corn oil emulsion

abnormal food preference
- given a choice, selection of a fat/protein diet declines with time

renal/urinary system phenotype

ethylmalonic aciduria
- relatively large amounts of ethylmalonate in the urine at 7-14 weeks of age
- ethylmalonate urinary excretion is higher than in controls

organic aciduria
- markedly increased urinary concentrations of ethylmalonic and methylsuccinic acids, and N-butyrylglycine in nonfasting and fasting mice, and remained elevated with or without medium chain triglyceride challenge
- ethylmalonate, methylsuccinate, and butyrylglycine urinary excretion is higher than in controls
- upon dosing with carnitine, mice excrete large amounts of butyryl-carnitine in the urine
- organic aciduria at 7-14 weeks of age, caused by relatively large amounts of n-butyrylglycine and ethylmalonate in the urine

cellular phenotype

abnormal fatty acid oxidation
- block in short-chain fatty acid oxidation shown by reduced butyryl-CoA dehydrogenation in liver mitochondria

Genotype: Hld/Hld
either: (involves: BALB/cByJ) or (involves: BALB/cJ)

cellular phenotype

abnormal neuronal migration

nervous system phenotype

abnormal neuronal migration

abnormal dendrite morphology
- cell bodies are located below the intrapyramidal mossy fiber layer
- abnormally positioned by being late-generated

ectopic hippocampus pyramidal cells
- located below the intrapyramidal layer; some of the ectopic cells have short, fine-caliber dendritic branches arising near the points of contact of the intrapyramidal mossy fibers

abnormal hippocampus morphology

abnormal hippocampus layer morphology
- this is secondary to a defect in neuronal migration
- Background Sensitivity - the anomaly is also seen in BALB/cByJ, F1 mice involving BALB sublines noted, and some CXB RI lines; C57BL/6J is considered wild-type for this feature

abnormal hippocampal mossy fiber morphology

abnormal hippocampus CA3 region morphology
- there is abnormal lamination of this cell layer resulting in superficial early generated neurons and deep late-generated neurons

Phenotype Information

Body Weight Information - JAX^® Mice Strain BALB/cByJ (001026)
Festing Inbred Strain Characteristics: BALB/c
JAX^® Physiological Data Summary [pdf]
Mouse Phenome Database / SNP Facility

References

Bentvelzen P; Daams JH; Hageman P; Calafat J. 1970. Genetic transmission of viruses that incite mammary tumor in mice. Proc Natl Acad Sci U S A 67(1):377-84PubMed: 4318784 MGI: J:24803
Champy MF; Selloum M; Zeitler V; Caradec C; Jung B; Rousseau S; Pouilly L; Sorg T; Auwerx J. 2008. Genetic background determines metabolic phenotypes in the mouse. Mamm Genome 19(5):318-31PubMed: 18392653 MGI: J:137669
Ebbesen P. 1971. Reticulosarcoma and amyloid development in BALB/c mice inoculated with syngeneic cells from young and old donors. J Natl Cancer Inst 47(6):1241-5PubMed: 4941118 MGI: J:24297
Heston WE; Vlahakis G. 1971. Mammary tumors, plaques, and hyperplastic alveolar nodules in various combinations of mouse inbred strains and the different lines of the mammary tumor virus. Int J Cancer 7(1):141-8PubMed: 4322934 MGI: J:24674
Hinsdale ME; Kelly CL; Wood PA. 1993. Null allele at Bcd-1 locus in BALB/cByJ mice is due to a deletion in the short-chain acyl-CoA dehydrogenase gene and results in missplicing of mRNA. Genomics 16(3):605-11PubMed: 8325633 MGI: J:12776
Petkov PM; Cassell MA; Sargent EE; Donnelly CJ; Robinson P; Crew V; Asquith S; Haar RV; Wiles MV. 2004. Development of a SNP genotyping panel for genetic monitoring of the laboratory mouse. Genomics 83(5):902-11PubMed: 15081119 MGI: J:89298
Roderick TH; Langley SH; Leiter EH. 1985. Some unusual genetic characteristics of BALB/c and evidence for genetic variation among BALB/c substrains. Curr Top Microbiol Immunol 122:9-18PubMed: 3899524 MGI: J:24307
Smith Richards BK; Belton BN; York B; Volaufova J. 2004. Mice bearing Acads mutation display altered postingestive but not 5-s orosensory response to dietary fat. Am J Physiol Regul Integr Comp Physiol 286(2):R311-9PubMed: 14592933 MGI: J:87779
Sundberg JP; Hanson CA; Roop DR; Brown KS; Bedigian HG. 1991. Myoepitheliomas in inbred laboratory mice. Vet Pathol 28(4):313-23PubMed: 1719689 MGI: J:22767
Wood PA; Amendt BA; Rhead WJ; Millington DS; Inoue F; Armstrong D. 1989. Short-chain acyl-coenzyme A dehydrogenase deficiency in mice. Pediatr Res 25(1):38-43PubMed: 2919115 MGI: J:14707
Wood PA; Hinsdale ME; Kelly CL. 1993. Molecular detection of the Bcd-1 null allele in BALB/cByJ mice by polymerase chain reaction: a simple assay for genetic monitoring Mouse Genome 91(2):342-44MGI: J:12812

Additional References

Bouwknecht JA; Paylor R. 2002. Behavioral and physiological mouse assays for anxiety: a survey in nine mouse strains. Behav Brain Res 136(2):489-501PubMed: 12429412 MGI: J:80397
Depis F; Kwon HK; Mathis D; Benoist C. 2016. Unstable FoxP3+ T regulatory cells in NZW mice. Proc Natl Acad Sci U S A 113(5):1345-50PubMed: 26768846 MGI: J:227903
Flaherty L; DiBiase K; Lynes MA; Seidman JG; Weinberger O; Rinchik EM. 1985. Characterization of a Q subregion gene in the murine major histocompatibility complex. Proc Natl Acad Sci U S A 82(5):1503-7PubMed: 2983348 MGI: J:7763
Glass AM; Coombs W; Taffet SM. 2013. Spontaneous cardiac calcinosis in BALB/cByJ mice. Comp Med 63(1):29-37PubMed: 23561935 MGI: J:307779
International Nomenclature Committee. 1952. COMMITTEE on Standardized Nomenclature for Inbred Strains of Mice Cancer Res 12(8):602-13PubMed: 14945054 MGI: J:166288
Michaelson J. 1983. Genetics of beta-2 microglobulin in the mouse. Immunogenetics 17(3):219-60PubMed: 6187676 MGI: J:7014
Moy SS; Nadler JJ; Young NB; Perez A; Holloway LP; Barbaro RP; Barbaro JR; Wilson LM; Threadgill DW; Lauder JM; Magnuson TR; Crawley JN. 2007. Mouse behavioral tasks relevant to autism: phenotypes of 10 inbred strains. Behav Brain Res 176(1):4-20PubMed: 16971002 MGI: J:138682
Sass B; Peters RL; Kelloff GJ. 1976. Differences in tumor incidence in two substrains of Claude BALB/c (BALB/cfCd) mice, emphasizing renal, mammary, pancreatic, and synovial tumors. Lab Anim Sci 26(5):736-41PubMed: 185454 MGI: J:24705
Smith BK; Andrews PK; West DB. 2000. Macronutrient diet selection in thirteen mouse strains. Am J Physiol Regul Integr Comp Physiol 278(4):R797-805PubMed: 10749765 MGI: J:61602
Southwick CH; Clark LH. 1966. Agressive behavior and exploratory activity in fourteen mouse strains. Am Zool 6:559MGI: J:23455
Teuscher C; Blankenhorn EP; Hickey WF. 1987. Differential susceptibility to actively induced experimental allergic encephalomyelitis and experimental allergic orchitis among BALB/c substrains. Cell Immunol 110(2):294-304PubMed: 2446778 MGI: J:149656

Additional - If1^l related

Additional - Acads^del-J related

Additional - Ahr^b-2 related

Additional - B2m^a related

Additional - Cdh23^ahl related

Additional - Hld related

Additional - Mdmg1 related

Technical Support

CONTACT TECHNICAL SUPPORT

Genotyping Protocols
- Sanger sequencing:H2 rs50413633
- Genotyping resources and troubleshooting
Inbred mouse strains are maintained through sibling (sister x brother) matings; no genotyping required.
Dietary Information
- LabDiet® 5K52 formulation (6% fat)
Breeding Considerations

This strain is a good breeder.
- Additional Breeding and Husbandry Support
Mating System
- Sibling x Sibling
Appearance
- albino
  Related Genotype: A/A Tyrp1^b/Tyrp1^b Tyr^c/Tyr^c
Citation
When using the BALB/cByJ mouse strain in a publication, please include JAX stock #001026 in your Materials and Methods section.

Animal Health Reports

Facility Barrier Level Descriptions

AX8 (Standard)

EM05 (Maximum)

RB09 (Maximum)

Pricing & Availability

Readily Available

Domestic
International

Live Mouse

Age

Genotype

Price

weeks

Cryorecovery - Pricing

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Mouse ES Cells	BALB/cByJ-PB150.18 mES cells	$695.00
Mouse ES Cells	BALB/cByJ AC383/GrsrJ mES cells	$995.00

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The Jackson Laboratory's Genotype Promise

The Jackson Laboratory has rigorous genetic quality control and mutant gene genotyping programs to ensure the genetic background of JAX® Mice strains as well as the genotypes of strains with identified molecular mutations. JAX® Mice strains are only made available to researchers after meeting our standards. However, the phenotype of each strain may not be fully characterized and/or captured in the strain data sheets. Therefore, we cannot guarantee a strain's phenotype will meet all expectations. To ensure that JAX® Mice will meet the needs of individual research projects or when requesting a strain that is new to your research, we suggest ordering and performing tests on a small number of mice to determine suitability for your particular project. We do not guarantee breeding performance and therefore suggest that investigators order more than one breeding pair to avoid delays in their research.

Terms Of Use

General Terms and Conditions

Questions about Terms of Use

Licensing Information

Phone: 207-288-6470

Email: TechTran@jax.org

Also Known As:BALB Bailey Jackson, BALB/c Bailey Jackson, CByJ

Genetic overview

Research Applications

Base Price

Important Note

Detailed Description

Development

Selected References

Hld

Allele Symbol: Hld

Ahrb-2

Allele Symbol: Ahrb-2

Cdh23ahl

Allele Symbol: Cdh23ahl

Acadsdel-J

Allele Symbol: Acadsdel-J

If1l

Allele Symbol: If1l

B2ma

Allele Symbol: B2ma

Mdmg1

Marker Symbol: Mdmg1

Disease Terms

Model with phenotypic similarity to human disease where etiologies involve orthologs. Human genes are associated with this disease. Orthologs of those genes appear in the mouse genotype(s).

Research Areas By Phenotype

This mouse can be used to support research in many areas including:

Genotype: Cdh23ahl related

Mammalian Phenotype Terms by Genotype

Genotype: Acadsdel-J/Acadsdel-Jinvolves: BALB/cByJ

homeostasis/metabolism phenotype

liver/biliary system phenotype

muscle phenotype

nervous system phenotype

behavior/neurological phenotype

renal/urinary system phenotype

cellular phenotype

Genotype: Hld/Hldeither: (involves: BALB/cByJ) or (involves: BALB/cJ)

cellular phenotype

nervous system phenotype

Phenotype Information

References

Additional References

Additional - If1l related

Additional - Acadsdel-J related

Additional - Ahrb-2 related

Additional - B2ma related

Additional - Cdh23ahl related

Additional - Hld related

Additional - Mdmg1 related

Genotyping Protocols

Dietary Information

Breeding Considerations

Mating System

Appearance

Citation

Animal Health Reports

Live Mouse

Cryorecovery - Pricing

Related Products and Services

Payment Terms and Conditions

The Jackson Laboratory's Genotype Promise

Terms Of Use

Licensing Information

Ahr^b-2

Allele Symbol: Ahr^b-2

Cdh23^ahl

Allele Symbol: Cdh23^ahl

Acads^del-J

Allele Symbol: Acads^del-J

If1^l

Allele Symbol: If1^l

B2m^a

Allele Symbol: B2m^a

Genotype: Cdh23^ahl related

Genotype: Acads^del-J/Acads^del-J
involves: BALB/cByJ

Genotype: Hld/Hld
either: (involves: BALB/cByJ) or (involves: BALB/cJ)

Additional - If1^l related

Additional - Acads^del-J related

Additional - Ahr^b-2 related

Additional - B2m^a related

Additional - Cdh23^ahl related