B10.A/(5R)SgSn-Galc^twi-2J/J

Stock number: 000978
Product name: twitcher 2 Jackson

Detailed description

These mice carry a spontaneous remutation at the Galc locus (see Stock No. 000845).

Development

The Galc^twi-2J mutation arose on the B10.A(5R)/SgSn congenic strain and was cryopreserved in 1984 by crossing male heterozygotes to C57BL/10ScSn females.

Allele

Symbol: Galc^twi-2J
Name: twitcher 2 Jackson
MGI accession ID: MGI:1856219
Generation method: Spontaneous
Marker symbol: Galc
Marker name: galactosylceramidase
Marker synonyms: 2310068B06Rik; A930008M05Rik; Gacy; galactocerebrosidase
Chromosome: 12
Strain of origin: B10.A-H2ⁱ⁵/(R5)SgSn
Molecular note: This allele was identified from the result of a complementation test with Galc^twi. Data defining the molecular lesion in this allele are not available.