These mice carry a spontaneous remutation at the Galc locus (see Stock No. 000845).
The Galctwi-2J mutation arose on the B10.A(5R)/SgSn congenic strain and was cryopreserved in 1984 by crossing male heterozygotes to C57BL/10ScSn females.
|Allele Name||twitcher 2 Jackson|
|Gene Symbol and Name||Galc, galactosylceramidase|
|Strain of Origin||B10.A-H2i5/(R5)SgSn|
|Molecular Note||This allele was identified from the result of a complementation test with Galctwi. Data defining the molecular lesion in this allele are not available.|