These mice carry the radiation induced Sig mutation. Heterozygotes have both eyes open at birth and slight hydrocephaly. Homozygotes die around birth with pronounced hydrocephaly and occasional syndactyly.
Genetic Background | Generation |
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000663 C57BL/6By |
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Allele Type | Gene Symbol | Gene Name |
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Radiation induced | Sig | sightless |
These mice carry the radiation induced Sig mutation. Heterozygotes have both eyes open at birth and slight hydrocephaly. Homozygotes die around birth with pronounced hydrocephaly and occasional syndactyly.
When using the sightless mouse strain in a publication, please cite the originating article(s) and include JAX stock #000836 in your Materials and Methods section.
Facility Barrier Level Descriptions
Service/Product | Description | Price |
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Heterozygous or Wild-type for Sig |
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The Jackson Laboratory has rigorous genetic quality control and mutant gene genotyping programs to ensure the genetic background of JAX® Mice strains as well as the genotypes of strains with identified molecular mutations. JAX® Mice strains are only made available to researchers after meeting our standards. However, the phenotype of each strain may not be fully characterized and/or captured in the strain data sheets. Therefore, we cannot guarantee a strain's phenotype will meet all expectations. To ensure that JAX® Mice will meet the needs of individual research projects or when requesting a strain that is new to your research, we suggest ordering and performing tests on a small number of mice to determine suitability for your particular project. We do not guarantee breeding performance and therefore suggest that investigators order more than one breeding pair to avoid delays in their research.
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