In(2)19Rk was induced by treatment of a DBA/2J male with 0.3 mg/kg TEM. This male was most likely then bred with a C57BL/6J female, but no further details on strain pedigree are available. This paracentric inversion has breakpoints in cytoband B and H1. Roderick and Hawes reported an anaphase bridge frequency of 0.609. The cryopreserved embryos were generated from the intercross of homozygotes so it is expected that the recovered pups will be homozygous. However, no molecular genotyping assay is available for this inversion. Researchers will be provided the cryorecovered mice and are encouraged to karyotype the mice received. A protocol for karyotyping can be found at the <a href="https://www.jax.org/research-and-faculty/tools/cytogenetic-and-down-syndrome-models-resource/protocols/blood-preps-protocol">Cytogenetic Models Resource</a>.

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