B6.C/(HW26C)ByJ

Stock number: 000759
Product name: HW26C
Research areas: Immunology, Inflammation and Autoimmunity Research

Description

This is one of a series of congenic strains developed by D.W. Bailey to isolate histocompatibility loci from the BALB/cBy strain onto a C57BL/6By genetic background. This strain may contain histocompatibility alleles identified in other congenic strains of this series.

Detailed description

Dubey et al. (1993) reported heightened NK cell activity in this Chromosome 4 congenic. Bailey (1985) reported a change, compared with the C57BL/6By host, in mandible shape, longbone length, and curvature and thickness of lower incisors.

Development

A portion of Chromosome 4 from BALB/cBy was backcrossed onto C57BL/6By by Dr. Don Bailey at The Jackson Laboratory. This congenic had reached generation N11 by 1985.

Allele

MGI accession ID: MGI:95888
Marker symbol: H16
Marker name: histocompatibility 16
Chromosome: 4

Allele

MGI accession ID: MGI:97233
Marker symbol: Mup1
Marker name: major urinary protein 1
Chromosome: 4

Allele

MGI accession ID: MGI:95968
Marker symbol: H21
Marker name: histocompatibility 21
Chromosome: 4

Allele

MGI accession ID: MGI:95967
Marker symbol: H20
Marker name: histocompatibility 20
Chromosome: 4

Allele

MGI accession ID: MGI:95887
Marker symbol: H15
Marker name: histocompatibility 15
Chromosome: 4