B6.C-H7^b/By Kit^W-50J/J

Stock number: 000560
Product name: dominant spotting 50 Jackson
Research areas: Cancer Research, Dermatology Research, Developmental Biology Research, Endocrine Deficiency Research, Immunology, Inflammation and Autoimmunity Research, Mouse/Human Gene Homologs, Neurobiology Research, Reproductive Biology Research, Research Tools, Sensorineural Research

Detailed description

These mice carry a spontaneous remutation at the Kit locus.

Development

The Kit^W-50J remutation occurred on B6.C-H7^b/By and cryopreserved in 1989 by mating homozygous males to C57BL/6J or C57BL/6By females.

Allele

Symbol: Kit^W-50J
Name: dominant spotting 50 Jackson
MGI accession ID: MGI:1856250
Generation method: Spontaneous
Marker symbol: Kit
Marker name: KIT proto-oncogene receptor tyrosine kinase
Marker synonyms: belly-spot; CD117; c-KIT; Dominant white spotting; Gsfsco1; Gsfsco5; Gsfsow3; MASTC; PBT; SCFR; SCO1; SCO5; SOW3; Steel Factor Receptor; Tr-kit
Chromosome: 5
Strain of origin: B6.C-H7^b/By
Molecular note: This spontaneous mutation was identified at The Jackson Laboratory.

Allele

MGI accession ID: MGI:96006
Marker symbol: H7
Marker name: histocompatibility 7
Marker synonyms: H-7
Chromosome: 9