B10.LP-H3^b/Sn

Stock number: 000421
Product name: B10.LP-H-3^b/Sn
Strain synonyms: B10LP
Research areas: Immunology, Inflammation and Autoimmunity Research

Detailed description

This B10 congenic strain carries the H3^b haplotype from LP/DiSn.

Development

This is one of the “Congenic Resistant” strains of mice developed by George D. Snell in his studies of histocompatibility. [Snell, G.D. 1978. In Origins of Inbred Mice (H.C. Morse III, ed.). Academic Press, New York.]

The H3^b haplotype from LP/DiSn was transferred onto C57BL/10ScSn by the equivalent of 13 generations before being maintained by sib matings. Embryos were cryopreserved in 1990.

Allele

MGI accession ID: MGI:1270153
Marker symbol: Zfp106
Marker name: zinc finger protein 106
Marker synonyms: Cd-1; H3a; SH3BP3; sirm; ZFP106; ZNF474
Chromosome: 2

Allele

MGI accession ID: MGI:95977
Marker symbol: H3
Marker name: histocompatibility 3
Marker synonyms: H-3
Chromosome: 2

Allele

MGI accession ID: MGI:88127
Marker symbol: B2m
Marker name: beta-2 microglobulin
Marker synonyms: AMYLD6; beta 2 microglobulin; beta2-m; IMD43; Ly-m11; MHC1D4
Chromosome: 2