Mutations at the Kit locus affect various aspects of hematopoiesis, the proliferation and migration of primordial germ cells and melanoblasts during development. The original KitW mutation and KitW-43J are lethal mutations when homozygous. KitW-43J heterozygotes exhibit borderline polycythemia, and phenotypic effects are almost indistinguishable from those of the classic KitW allele.

These mice carry a spontaneous remutation at the Kit locus characterized by homozygous lethality and white belly spotting and polycythemia in heterozygotes.

Typically mice are recovered in 12-16 weeks. Contact Customer Service to place an order or for more information.

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