Genetic Background | Generation |
---|---|
|
Allele Type | Gene Symbol | Gene Name |
---|---|---|
Spontaneous | Ph | patch deletion region |
Allele Name | patch |
---|---|
Allele Type | Spontaneous |
Allele Synonym(s) | PdgfrPh |
Gene Symbol and Name | Ph, patch deletion region |
Gene Synonym(s) | |
Strain of Origin | C57BL/Gr |
Chromosome | 5 |
General Note | Repulsion double heterozygotes of Ph and the allele KitW-ct at the closely linked Kit locus (Ph +/+ KitW-ct) are more anemic than Kit |
Molecular Note | A deletion region including the Pdgfra gene. Precise breakpoints have not been mapped, but does not extend into the coding sequences of the adjacent Kit gene. However, expression of Kit is altered in these mutants. |
When using the C57BL/6J-Ph/J mouse strain in a publication, please cite the originating article(s) and include JAX stock #000118 in your Materials and Methods section.
Facility Barrier Level Descriptions
Service/Product | Description | Price |
---|---|---|
Heterozygous or Wild-type for Ph |
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The Jackson Laboratory has rigorous genetic quality control and mutant gene genotyping programs to ensure the genetic background of JAX® Mice strains as well as the genotypes of strains with identified molecular mutations. JAX® Mice strains are only made available to researchers after meeting our standards. However, the phenotype of each strain may not be fully characterized and/or captured in the strain data sheets. Therefore, we cannot guarantee a strain's phenotype will meet all expectations. To ensure that JAX® Mice will meet the needs of individual research projects or when requesting a strain that is new to your research, we suggest ordering and performing tests on a small number of mice to determine suitability for your particular project. We do not guarantee breeding performance and therefore suggest that investigators order more than one breeding pair to avoid delays in their research.
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