Mice exhibit hyperprolinemia and hyperprolinuria. Proline levels in the blood are increased by seven-fold in comparison to the two parental strains, C57BL/6J and 129P1/ReJ. Proline is detected in the urine of all PRO/ReJ mice, however, it is undetectable in the parental strains. This strain may be useful in studies of human hyperprolinemia.
Mice exhibit hyperprolinemia and hyperprolinuria. Proline levels in the blood are increased by seven-fold in comparison to the two parental strains, C57BL/6J and 129P1/ReJ. Proline is detected in the urine of all PRO/ReJ mice, however, it is undetectable in the parental strains. This strain may be useful in studies of human hyperprolinemia.
This inbred strain was developed from a cross between 129P1/ReJ and C57BL/6J followed by selection for the coat colors nonagouti (a), chinchilla (c-ch) and pink eye (p).
Currently there are no related genes or alleles for this strain.
When using the PRO/ReJ mouse strain in a publication, please include JAX stock #000059 in your Materials and Methods section.
Facility Barrier Level Descriptions
Service/Product | Description | Price |
---|---|---|
Homozygous, 1 pair minimum |
Frozen Mouse Embryo | PRO/ReJ Frozen Embryos | $2595.00 |
Frozen Mouse Embryo | PRO/ReJ Frozen Embryos | $2595.00 |
Frozen Mouse Embryo | PRO/ReJ Frozen Embryos | $3373.50 |
Frozen Mouse Embryo | PRO/ReJ Frozen Embryos | $3373.50 |
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The Jackson Laboratory has rigorous genetic quality control and mutant gene genotyping programs to ensure the genetic background of JAX® Mice strains as well as the genotypes of strains with identified molecular mutations. JAX® Mice strains are only made available to researchers after meeting our standards. However, the phenotype of each strain may not be fully characterized and/or captured in the strain data sheets. Therefore, we cannot guarantee a strain's phenotype will meet all expectations. To ensure that JAX® Mice will meet the needs of individual research projects or when requesting a strain that is new to your research, we suggest ordering and performing tests on a small number of mice to determine suitability for your particular project. We do not guarantee breeding performance and therefore suggest that investigators order more than one breeding pair to avoid delays in their research.
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