C57BL/6J-A^w-J/J

Stock number: 000051
Product name: B6 agouti
Research areas: Dermatology Research

Description

Mice are agouti (hairs are black with a subapical yellow band) with a cream or white belly. Females may be used as foster mothers for ovary transplantation of mutations maintained in a/a strains because A^w-J is dominant to the nonagouti a.

Detailed description

Mice are agouti (hairs are black with a subapical yellow band) with a cream or white belly. Females may be used as foster mothers for ovary transplantation of mutations maintained in a/a strains because A^w-J is dominant to the nonagouti a. Since a to A^w is a common mutation, strains possessing this mutation in laboratory stock may not be of a common origin.

Development

Mutation discovered in the C57BL/6J strain at The Jackson Laboratory in the early 1960's.

Allele

Symbol: A^w-J
Name: white bellied agouti Jackson
MGI accession ID: MGI:1855946
Generation method: Spontaneous
Synonyms: A^WJ
Marker symbol: a
Marker name: nonagouti
Marker synonyms: agouti; agouti signal protein; AGSW; AGTI; AGTIL; As; ASP; SHEP9
Chromosome: 2
Strain of origin: C57BL/6J