How to cite this resource
Please reference the Mouse Resource for Craniofacial Research in citations acknowledging use of the resource.
This resource grew out of two separate NIH programs. The FaceBase Consortium, a five-year initiative to construct the middle region of the human face and precisely define the genetics underlying common developmental disorders of the human face, provided support from 2009-2014 (DE020052). Separately, development of spontaneous mutant models of craniofacial disorders began under an R01 (EY015073) between 2009-2013. Combined, these two programs formed the foundation for a diverse resource of models for craniofacial research.
Current support for the resource comes from The Jackson Laboratory and the sale of mice.
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Selected publications
Curtain M, Heffner CS, Maddox DM, Gudis P, Donahue LR, Murray SA. 2015. A novel allele of Alx4 results in reduced Fgf10 expression and failure of eyelid fusion in mice. Mamm Genome. 2015 Apr;26(3-4):173-80. doi: 10.1007/s00335-015-9557-z. Epub 2015 Feb 12.PMID: 25673119
Murray SA, Eppig JT, Smedley D, Simpson EM, Rosenthal N. 2012. Beyond knockouts: cre resources for conditional mutagenesis. Mamm Genome 23(9-10):587-599. PMCID: PMC3655717
Hochheiser H, Aronow BJ, Artinger K, Beaty TH, Brinkley JF, Chai Y, Clouthier D, Cunningham ML, Dixon M, Donahue LRD, Fraser SE, Iwata J, Marazita ML, Murray JC, Murray SA, Postlethwait J, Potter S, Shapiro L, Spritz R, Visel A, Weinberg SM, Trainor PA. 2011. The FaceBase Consortium: a comprehensive program to facilitate craniofacial research. Dev Biol 355(2):175-82. PMCID: PMC3440302
Murray SA. 2011. Mouse resources for craniofacial research. Genesis 49(4):190-9. PMCID: PMC3610317
Fairfield H et al. 2011. Mutation discovery in mice by whole exome sequencing. Genome Biol. 12(9):R86. PMCID: PMC3308049.
Keane TM et al. 2011. Mouse genomic variation and its effect on phenotypes and gene regulation. Nature 477:289-294. PMCID: PMC3276836.
Odgren PR, Pratt CH, Mackay CA, Mason-Savas A , Curtain M, Shopland L, Ichicki T, Sundberg JP , Donahue LR. 2010. Disheveled hair and ear (Dhe), a spontaneous mouse Lmna mutation modeling human laminopathies. PLoS One Apr1:5(4):e9959.PMCID:2848607.