Cre is expressed from the "K<sub>v</sub>3.2" promoter in these transgenic mice.  When crossed with a lacZ reporter strain, strong expression was seen in the rostral and midline thalamic nuclei (xiphoid, reunions, rhomboid, centromedial, intermediodorsal, paraventricular, paracentral, centrolateral, submedius, mediodorsal, lateral dorsal, anteromedial, suprageniculate, and Paratenial).  Moderate expression was observed in other thalamic nuclei: anteroventral, anterodorsal, ventral lateral, ventral anterior, parafascicular, and posterior thalamic group.  Weak expression was observed in the lateral posterior,dorsal lateral geniculate, medial geniculate, and ventral posterior thalamic nuclei.
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Strong activity was observed also in ventral medial and dorsal medial hypothalamic nuclei, pontine reticular nucleus, mesencephalic fifth, and 12th cranial nerve nuclei.  Moderate recombination was also present in the superficial piriform cortex, indusium griseum, dorsal endopiriform nucleus, medial and median preoptic hypothalamic nuclei, medial vistibular nucleus, ventral cochlear nucleus, nucleus of trapezoid body, and abducens nucleus.  Very small numbers of neurons expressed in the lateral septum, locus coeruleus, substantia nigra par reticulata, and parabrachial nucleus.    

Cre is expressed from the Kcnc2 (potassium voltage gated channel, Shaw-related subfamily, member 2, "Kv3.2") promoter in these transgenic mice. When crossed with a lacZ reporter strain, expression is seen in specific subsets of thalamic nuclei and other locations in the brain.

Typically mice are recovered in 12-16 weeks. Contact Customer Service to place an order or for more information.

Typically mice are recovered in 12-16 weeks. <a target="_blank" href="https://www.jax.org/jax-mice-and-services/customer-support" rel="noreferrer">Contact Customer Service</a> to place an order or for more information.