This new video from The Cox Lab video offers an inside look at the research goals of Amy Hicks, a postdoctoral associate who is studying the relationship between the heart and nerves in this devastating genetic disease.
Rett syndrome results from mutations in MeCP2 that cause peripheral and central nervous system deficits, including a decreased sensitivity to pain, or hypoalgesia. A March 2016 study investigates the impact of mutations in MeCP2 on pain modulation and hypoalgesia in a mouse model of Rett syndrome.
Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, is a progressive and fatal neurodegenerative disease that affects motor neurons. A January 2016 study published in Neurobiology of Disease describes a copper-based therapy that is quick-acting, safe, and effective in prolonging survival and even reversing disease signs in SODG93A ALS mice.