HSA: integrating multi-track Hi-C data for genome-scale reconstruction of 3D chromatin structure

Integrating multi-track Hi-C data for genome-scale reconstruction of 3D chromatin structure

HSA is a flexible tool that can jointly analyze multiple contact maps from Hi-C experiments to infer the 3D chromatin structure of the genome.

Citation: Zou C, Zhang Y, Ouyang Z. (2016) HSA: integrating multi-track Hi-C data for genome-scale reconstruction of 3D chromatin structure. Genome Biology, 17:40.

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Press ReleaseApril 16, 2019
A thorough characterization of structural variants in human genomes
A recent study used multiple advanced technologies to dive deeper into the human genome than ever before to comprehensively characterize the structural variants present in three families, and what their functional consequences might be.
Research HighlightApril 11, 2019
Mechanisms of sound perception
A new paper in PNAS offers new insights into the proteins that influence our ability to perceive sound direction and intensity.
Search MagazineMarch 19, 2019
Making a difference for rural cancer patients
Dr. Jens Rueter and the Maine Cancer Genomics Initiative are providing advanced genomic tools to oncology practices throughout Maine.
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Exploring the hypothalamus one neuron at a time
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Research HighlightApril 16, 2019
Genetically diverse mice show human-like responses to heart attack
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Press ReleaseApril 01, 2019
Premature cellular aging and multiple sclerosis
Research led by the UConn School of Medicine and JAX shows that senescence, a cellular aging process, is associated with an aggressive form of multiple sclerosis (MS). The finding explains a mechanism for MS disease progression as well as indicating a promising avenue for therapy development.
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Research HighlightMarch 12, 2019
A closer look at structural variants in the genome
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Research HighlightMarch 08, 2019
Long-range connectivity and gene regulation networks
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HSA: integrating multi-track Hi-C data for genome-scale reconstruction of 3D chromatin structure

Faculty & Staff

Zhengqing Ouyang, Ph.D.

A thorough characterization of structural variants in human genomes

Mechanisms of sound perception

Making a difference for rural cancer patients

Exploring the hypothalamus one neuron at a time

Genetically diverse mice show human-like responses to heart attack

Premature cellular aging and multiple sclerosis

A closer look at structural variants in the genome

Long-range connectivity and gene regulation networks