HSA: integrating multi-track Hi-C data for genome-scale reconstruction of 3D chromatin structure

Integrating multi-track Hi-C data for genome-scale reconstruction of 3D chromatin structure

HSA is a flexible tool that can jointly analyze multiple contact maps from Hi-C experiments to infer the 3D chromatin structure of the genome.

Citation: Zou C, Zhang Y, Ouyang Z. (2016) HSA: integrating multi-track Hi-C data for genome-scale reconstruction of 3D chromatin structure. Genome Biology, 17:40.

Visit HSA

Research HighlightOctober 11, 2018
Stuck in a dangerous cycle
Paper provides important insight for B-cell lymphomagenesis from mouse models to human disease.
Press ReleaseOctober 09, 2018
'Nonstick' molecule enables correct neural development
DSCAM interacts with other cell adhesion molecules to prevent their running amok.
Search MagazineOctober 09, 2018
Of mighty mice and men
Pioneering scientist Se-Jin Lee, a leader in the study of muscle development, moves his groundbreaking research program to JAX.
Press ReleaseSeptember 25, 2018
Brain cancer’s lethal differences: tracking extra DNA
Postdoctoral Associate Eunhee Yi has been awarded a $100,000 fellowship from the American Brain Tumor Association to discover how glioblastoma becomes so aggressive.

Tech CornerOctober 11, 2018
Precision medicine and making sense of data
JAX professor calls for concerted effort to align data across patients and systems with comparable and consistent formats and contextual meaning.
Press ReleaseOctober 09, 2018
Advancing therapeutic gene editing
NIH awards $3.5M to JAX under multi-institution Somatic Cell Genome Editing program.
Press ReleaseOctober 02, 2018
Addiction: The microbiome link
The National Institute on Drug Abuse has made a $4M grant to JAX scientists to explore the roles of the microbiome and genetics in substance use disorders.
Blog PostSeptember 25, 2018
American Cancer Society colon cancer screening guidelines
Could early colorectal cancer screening recommended by the American Cancer Society identify more people at high risk for hereditary cancer?
- Colon and Rectal Cancer
- Cancer

HSA: integrating multi-track Hi-C data for genome-scale reconstruction of 3D chromatin structure

Faculty & Staff

Zhengqing Ouyang, Ph.D.

Stuck in a dangerous cycle

'Nonstick' molecule enables correct neural development

Of mighty mice and men

Brain cancer’s lethal differences: tracking extra DNA

Precision medicine and making sense of data

Advancing therapeutic gene editing

Addiction: The microbiome link

American Cancer Society colon cancer screening guidelines