The Verhaak Lab
Brain tumors, sequencing, computational biology.
Brain tumors, sequencing, computational biology.
Press Release
July 11, 2017
New collaboration expands access to leading-edge research capabilities to find new treatments for life-threatening diseases.
The Search Magazine Article
July 10, 2017
Kevin Johnson, Ph.D., a postdoc in the Verhaak lab, recently received the prestigious American Cancer Society Postdoctoral Fellowship Award.
In a recent PLOSOne study, a research team led by Dr. Abraham Eisenstock at the University of Missouri lays the groundwork for further developing Salmonella strains to treat prostate cancer.
Effective interpretation and identification of causative and actionable mutations in disease states is still a major hurdle to the delivery of personalized genomics.
Press Release
July 10, 2017
A JAX-led research team detects gene expression patterns distinct from those of the surrounding immune cells, and characterizes the effects of chemotherapy and radiation treatments.
Press Release
January 30, 2017
Cancer cells hijack a mechanism that enables stem cells and germ cells to continue dividing, by reactivating telomerase. A research team led by JAX Professor Roel Verhaak reports on the discovery that, in about 35 percent of cancers, TERT promoter methylation is the key to cancer cells' success in maintaining telomeres and surviving.
A recent Immunity (Solmon et al, 2016) article uncovers a new combinatorial immuno-oncology approach to overcome melanoma resistance to BRAF- and immune checkpoint inhibitor single drug treatments.
A 2014 report in PLoS One describes the generation of an improved host for syngeneic tumor transplantation studies using luciferase- and EGFP-labeled tumor cells. Dubbed “Glowing Head” mice, the new models overcome several problems associated with immune responses to the bioluminescent reporters.