The Li Lab

Assessing the performance of next-generation sequencing techniques in accurate genome/epigenome/transcriptome profiling and understanding the clinical and functional role of epigenome heterogeneity in the cancer evolution.

Our research focus

My research interest is to understand the inner workings of cancer cells – the genetic and epigenetic heterogeneity that drive cancer initiation and progression. We utilize computational algorithms and multi-omics methodologies to identify and characterize the essential epigenetic lesions that guide cancer cells to evolve and escape anti-cancer therapy. The ultimate goal is to develop novel methods to predict and address tumor evolution.