Olga Anczukow-Camarda, Ph.D.
Associate Professor

Investigates how alternative RNA splicing contributes to cancer with the goal of identifying novel clinical biomarkers and targets for precision medicine.

Christine Beck, Ph.D.
Assistant Professor

Investigates the mechanisms and consequences of genomic rearrangements with a focus on repetitive elements. These lines of inquiry could find regions prone to instability in human cancers and lead to targets for therapy.

Ewelina Bolcun-Filas, Ph.D.
Associate Professor

Researches meiosis, the mechanisms of DNA damage detection and repair during normal development of gametes, and implications for fertility of cancer patients after radiation and chemotherapy.

Robert E. Braun, Ph.D.
Professor

Researches the mechanisms that regulate germline stem cell fate, a fundamental issue in cancer biology.

Carol Bult, Ph.D.
Professor

Integrates computation and informatics with biomedical research. Makes knowledge about mouse models of human cancer  FAIR (findable, accessible, interoperable, reusable).

Gregory Carter, Ph.D.
Professor

Develops computational strategies using genetic data to understand complex genetic systems involving multiple genes and environmental factors.

Chih-Hao "Lucas" Chang, Ph.D.
Assistant Professor

Researches the complex interactions of the tumor microenvironment with the host immune system. Focuses on immunometabolism of T and B cells, which play a vital role in fighting tumors.

Elissa J. Chesler, Ph.D.
Sr. Director, Integrative Data Science, Professor

Researches systems genetics and integrative genomics tools and resources, such as Collaborative Cross and Diversity Outbred mouse populations, and the GeneWeaver.org integrative functional genomics web resource which have broad applicability to cancer genetics and genomics.

Jeffrey Chuang, Ph.D.
Professor

Computational studies of cancer image and sequence data to improve treatment outcomes.

Gary Churchill, Ph.D.
Professor

Employs a systems approach to investigate the genetics of health and disease and complex disease-related traits in the mouse. Co-director of the Jackson Aging Center, a Nathan Shock Center of Excellence in the Basic Biology of Aging.

David Harrison, Ph.D.
Professor

Age is the most important risk factor for most cancers in both human beings and in mouse models. Researches interventions that retard mammalian aging.

Ching Lau, M.D., Ph.D.
Professor

Specializes in pediatric brain and bone tumor research. Clinical interests include neuro-oncology, solid tumors, and osteosarcoma.

Charles Lee, Ph.D., FACMG
Scientific Director JAXGM and Professor

Studies structural genomic variation in human biology, evolution and disease.

Se-Jin Lee, M.D., Ph.D.
Professor

Attempts to exploit the biological properties of myostatin to develop novel therapeutic strategies for treating patients with muscle degenerative and wasting conditions resulting from diseases like cancer.

Sheng Li, Ph.D.
Associate Professor

Applies data integration and machine learning to advance the frontiers of cancer epigenomics and evolution.

Shuzhao Li, Ph.D.
Associate Professor

Metabolomics for precision medicine; ImmunoMetabolomics and multi-omics modeling of immune system. This revolutionary information fills a major gap between genome and environment, with broad applications to diseases and precision medicine.

Edison Liu, M.D.
Professor

Conducts research focused on the functional genomics of breast cancer through an exploration of the entire genomic space.

Francesca Menghi, Ph.D.
Associate Research Scientist

Studies critical genomic changes implicated in ovarian and breast cancers.

Steven Munger, Ph.D.
Associate Professor

Conducting research to elucidate and compare the transcriptional network structure and dynamics driving organogenesis.

Steven Murray, Ph.D.
Associate Professor

Develops novel mouse models of human disease and provides these resources to the scientific community. Employs conditional mutagenesis and forward genetics to interrogate the role of individual genes in development and disease.

Julia Oh, Ph.D.
Associate Professor

 Uses diverse tools like genomics and synthetic biology to investigate our microbiome’s role in our health and engineer therapeutics.

Karolina Palucka, M.D., Ph.D.
Director, Jax Cancer Center and Professor

Conducts research to understand how vaccines work and to define precisely the immune mechanisms that underlie vaccination, with a focus on cancer immunotherapies.

Laura Reinholdt, Ph.D.
Associate Professor

Focuses on comparative and functional mammalian genomics, reproductive development and stem cell biology.

Guangwen "Gary" Ren, Ph.D.
Assistant Professor

Focuses on comparative and functional mammalian genomics, reproductive development and stem cell biology.

Martin Ringwald, Ph.D.
Associate Professor

Develops and enhances the Gene Expression Database (GXD), which captures, integrates and displays mouse developmental expression data generated world-wide.

Peter Robinson, M.D., M.S.
Professor

Develops algorithms and software for the analysis of exome and genome sequences.

Paul Robson, Ph.D.
Professor

Studies cell-type composition in human solid tumors directly and derive models from these for functional analyses.

Jens Rueter, M.D.
JAX Chief Medical Officer, Medical Director MCGI

Provides direction, leadership and strategy for JAX’s translational and clinical research activities and clinically-oriented operations.

David Serreze, Ph.D.
Professor

Researches the genetic basis for immunological tolerance. Generating anti-tumor immune responses requires the transient induction of a form of autoimmunity.

Lenny Shultz, Ph.D.
Professor

Investigates human immunological diseases and malignancy through the development and leveraging of novel humanized mouse models.

Bill Skarnes, Ph.D.
Professor, Cellular Engineering

Exploits new genome-editing technology to study gene function and to model disease in human stem cells.

Jennifer Trowbridge, Ph.D.
Professor

Researches regulation of stem cells in the blood in normal development, aging and leukemia transformation.

Duygu Ucar, Ph.D.
Associate Professor

Develops computational models using genome datasets to study gene regulation and identify hypotheses for genomic medicine.

Derya Unutmaz, M.D.
Professor

Researches the mechanisms of human T cell differentiation, activation and regulation in the contexts of normal immune response, diseases and aging.

Frederick Varn, Ph.D.
Assistant Professor

Employs genomic and computational approaches to investigate how the immune response shapes brain tumor development.

Eric Wang, Ph.D.
Assistant Professor

Investigates mechanisms of drug resistance in hematological malignancies with the main goal to develop new therapeutic strategies and providing a blueprint for clinically relevant biomarkers.

Chia-Lin Wei, Ph.D.
Professor and Director of Genome Technologies

Develops and provides genomics and sequencing services for JAX researchers.