CSNA Publications

  1. Reynolds T, Johnson EC, Huggett SB, Bubier JA, Palmer RHC, Agrawal A, Baker EJ, Chesler EJ. Interpretation of psychiatric genome-wide association studies with multispecies heterogeneous functional genomic data integration. Neuropsychopharmacology. 2021 Jan;46(1):86-97. https://mouseion.jax.org/stfb2021/1/
  2. Kim SM, Vadnie CA, Philip VM, Gagnon LH, Chowdari KV, Chesler EJ, McClung CA, Logan RW. High-throughput measurement of fibroblast rhythms reveals genetic heritability of circadian phenotypes in diversity outbred mice and their founder strains. Sci Rep. 2021 Jan 28;11(1):2573. https://mouseion.jax.org/stfb2021/36/
  3. Ouellette AR, Neuner SM, Dumitrescu L, Anderson LC, Gatti DM, Mahoney ER, Bubier JA, Churchill G, Peters L, Huentelman MJ, Herskowitz JH, Yang HS, Smith AN, Reitz C, Kunkle BW, White CC, De Jager PL, Schneider JA, Bennett DA, Seyfried NT, Chesler EJ, Hadad N, Hohman TJ, Kaczorowski CC. Cross-Species Analyses Identify Dlgap2 as a Regulator of Age-Related Cognitive Decline and Alzheimer's Dementia. Cell Rep. 2020 Sep 1;32(9):108091. doi: 10.1016/j.celrep.2020.108091. PubMed PMID: 32877673; PubMed Central PMCID: PMC7502175.
  4. Bubier JA, He H, Philip VM, Roy T, Hernandez CM, Bernat R, Donohue KD, O"Hara BF, Chesler EJ. Genetic variation regulates opioid-induced respiratory depression in mice. Scientific Reports. 2020 September; 10(1):14970. doi: 10.1038/s41598-020-71804-2.
  5. Skelly DA, Czechanski A, Byers C, Aydin S, Spruce C, Olivier C, Choi K, Gatti DM, Raghupathy N, Keele GR, Stanton A, Vincent M, Dion S, Greenstein I, Pankratz M, Porter DK, Martin W, O'Connor C, Qin W, Harrill AH, Choi T, Churchill GA, Munger SC, Baker CL, Reinholdt LG. Mapping the Effects of Genetic Variation on Chromatin State and Gene Expression Reveals Loci That Control Ground State Pluripotency. Cell Stem Cell. 2020 Sep 3;27(3):459-469.e8. doi: 10.1016/j.stem.2020.07.005. Epub 2020 Aug 13. PubMed PMID: 32795400; PubMed Central PMCID: PMC7484384.
  6. Reynolds T, Johnson EC, Huggett SB, Bubier JA, Palmer RHC, Agrawal A, Baker EJ, Chesler EJ. Interpretation of psychiatric genome-wide association studies with multispecies heterogeneous functional genomic data integration. Neuropsychopharmacology. 2020 Aug 13. doi: 10.1038/s41386-020-00795-5.[Epub ahead of print] Review. PubMed PMID: 32791514.
  7. Seney ML, Logan RW. Critical roles for developmental hormones and genetic sex in stress-induced transcriptional changes associated with depression. Neuropsychopharmacology. 2020 Aug 7. doi: 10.1038/s41386-020-00792-8. [Epub ahead of print] PubMed PMID: 32770141.
  8. Huggett SB, Bubier JA, Chesler EJ, Palmer RHC. Do gene expression findings from mouse models of cocaine use recapitulate human cocaine use disorder in reward circuitry? Genes Brain Behav. 2020 Jul 27; e12689. doi: 10.1111/gbb.12689. [Epub ahead of print] PubMed PMID: 32720468; NIHMSID:NIHMS1622397.
  9. Bubier JA, Philip VM, Quince C, Campbell J, Zhou Y, Vishnivetskaya T, Duvvuru S, Blair RH, Ndukum J, Donohue KD, Foster CM, Mellert DJ, Weinstock G, Culiat CT, O'Hara BF, Palumbo AV, Podar M, Chesler EJ. A Microbe Associated with Sleep Revealed by a Novel Systems Genetic Analysis of the Microbiome in Collaborative Cross Mice. Genetics. 2020 Mar;214(3):719-733. doi:10.1534/genetics.119.303013. Epub 2020 Jan 2. PubMed PMID: 31896565; PubMed Central PMCID: PMC7054020.
  10. Datta U, Schoenrock SE, Bubier JA, Bogue MA, Jentsch JD, Logan RW, Tarantino LM, Chesler EJ. Prospects for finding the mechanisms of sex differences in addiction with human and model organism genetic analysis. Genes Brain Behav. 2020 Mar;19(3):e12645. doi: 10.1111/gbb.12645. Epub 2020 Feb 11. Review. PubMed PMID: 32012419; PubMed Central PMCID: PMC7060801
  11. Paden W, Barko K, Puralewski R, Cahill KM, Huo Z, Shelton MA, Tseng GC, Logan RW, Seney ML. Sex differences in adult mood and in stress-induced transcriptional coherence across mesocorticolimbic circuitry. Transl Psychiatry. 2020 Feb 6;10(1):59. doi: 10.1038/s41398-020-0742-9. PubMed PMID: 32066699; PubMed Central PMCID: PMC7026087.
  12. Bubier JA, Philip VM, Dickson PE, Mittleman G, Chesler EJ. Discovery of a Role for Rab3b in Habituation and Cocaine Induced Locomotor Activation in Mice Using Heterogeneous Functional Genomic Analysis. Front Neurosci. 2020;14:721. doi: 10.3389/fnins.2020.00721. eCollection 2020. PubMed PMID: 32742255; PubMed Central PMCID: PMC7364128.
  13. Calvo M, Davies AJ, Hébert HL, Weir GA, Chesler EJ, Finnerup NB, Levitt RC, Smith BH, Neely GG, Costigan M, Bennett DL. The Genetics of Neuropathic Pain from Model Organisms to Clinical Application. Neuron. 2019 Nov 20;104(4):637-653. doi: 10.1016/j.neuron.2019.09.018. Review. PubMed PMID: 31751545; PubMed Central PMCID: PMC6868508.
  14. Recla JM, Bubier JA, Gatti DM, Ryan JL, Long KH, Robledo RF, Glidden NC, Hou G, Churchill GA, Maser RS, Zhang ZW, Young EE, Chesler EJ, Bult CJ. Genetic mapping in Diversity Outbred mice identifies a Trpa1 variant influencing late-phase formalin response. Pain. 2019 Aug;160(8):1740-1753. doi: 10.1097/j.pain.0000000000001571. PubMed PMID: 31335644; PubMed Central PMCID: PMC6668363.
  15. Boehm FJ, Chesler EJ, Yandell BS, Broman KW. Testing Pleiotropy vs. Separate QTL in Multiparental Populations. G3 (Bethesda). 2019 Jul 9;9(7):2317-2324. doi: 10.1534/g3.119.400098. PubMed PMID: 31092608; PubMed Central PMCID: PMC6643884.
  16. Skelly DA, Raghupathy N, Robledo RF, Graber JH, Chesler EJ. Reference Trait Analysis Reveals Correlations Between Gene Expression and Quantitative Traits in Disjoint Samples. Genetics. 2019 Jul;212(3):919-929. doi: 10.1534/genetics.118.301865. Epub 2019 May 21. PubMed PMID: 31113812; PubMed Central PMCID: PMC6614885.
  17. Saul MC, Philip VM, Reinholdt LG, Chesler EJ. High-Diversity Mouse Populations for Complex Traits. Trends Genet. 2019 Jul;35(7):501-514. doi: 10.1016/j.tig.2019.04.003. Epub 2019 May 24. Review. PubMed PMID: 31133439; PubMed Central PMCID: PMC6571031.
  18. Parekh PK, Logan RW, Ketchesin KD, Becker-Krail D, Shelton MA, Hildebrand MA, Barko K, Huang YH, McClung CA. Cell-Type-Specific Regulation of Nucleus Accumbens Synaptic Plasticity and Cocaine Reward Sensitivity by the Circadian Protein, NPAS2. J Neurosci. 2019 Jun 12;39(24):4657-4667. doi: 10.1523/JNEUROSCI.2233-18.2019. Epub 2019 Apr 8. PubMed PMID: 30962277; PubMed Central PMCID: PMC6561687.
  19. Barko K, Paden W, Cahill KM, Seney ML, Logan RW. Sex-Specific Effects of Stress on Mood-Related Gene Expression. Mol Neuropsychiatry. 2019 Jun;5(3):162-175. doi: 10.1159/000499105. Epub 2019 Apr 30. PubMed PMID: 31312637; PubMed Central PMCID: PMC6597924.
  20. Gunduz-Cinar O, Brockway E, Lederle L, Wilcox T, Halladay LR, Ding Y, Oh H, Busch EF, Kaugars K, Flynn S, Limoges A, Bukalo O, MacPherson KP, Masneuf S, Pinard C, Sibille E, Chesler EJ, Holmes A. Identification of a novel gene regulating amygdala-mediated fear extinction. Mol Psychiatry. 2019 Apr;24(4):601-612. doi: 10.1038/s41380-017-0003-3. Epub 2018 Jan 8. PubMed PMID: 29311651; PubMed Central PMCID: PMC6035889.
  21. 19. Donvito G, Piscitelli F, Muldoon P, Jackson A, Vitale RM, D'Aniello E, Giordano C, Ignatowska-Jankowska BM, Mustafa MA, Guida F, Petrie GN, Parker L, Smoum R, Sim-Selley L, Maione S, Lichtman AH, Damaj MI, Di Marzo V, Mechoulam R. N-Oleoyl-glycine reduces nicotine reward and withdrawal in mice. Neuropharmacology. 2019 Apr;148:320-331. doi:10.1016/j.neuropharm.2018.03.020. Epub 2018 Mar 19. PubMed PMID: 29567093; PubMed Central PMCID: PMC6408981.
  22. Dickson PE, Roy TA, McNaughton KA, Wilcox TD, Kumar P, Chesler EJ. Systems genetics of sensation seeking. Genes Brain Behav. 2019 Mar;18(3):e12519. doi: 10.1111/gbb.12519. Epub 2018 Oct 8. PubMed PMID: 30221471; PubMed Central PMCID: PMC6399063.
  23. Geuther BQ, Deats SP, Fox KJ, Murray SA, Braun RE, White JK, Chesler EJ, Lutz CM, Kumar V. Robust mouse tracking in complex environments using neural networks. Commun Biol. 2019;2:124. doi: 10.1038/s42003-019-0362-1. eCollection 2019. PubMed PMID: 30937403; PubMed Central PMCID: PMC6440983.
  24. Capri KM, Maroni MJ, Deane HV, Concepcion HA, DeCourcey H, Logan RW, Seggio JA. Male C57BL6/N and C57BL6/J Mice Respond Differently to Constant Light and Running-Wheel Access. Front Behav Neurosci. 2019;13:268. doi: 10.3389/fnbeh.2019.00268. eCollection 2019. PubMed PMID: 31920578; PubMed Central PMCID: PMC6914853.
  25. Logan RW, McClung CA. Rhythms of life: circadian disruption and brain disorders across the lifespan. Nat Rev Neurosci. 2019 Jan;20(1):49-65. doi: 10.1038/s41583-018-0088-y. Review. PubMed PMID: 30459365; PubMed Central PMCID: PMC6338075.
  26. Tuttle AH, Philip VM, Chesler EJ, Mogil JS. Comparing phenotypic variation between inbred and outbred mice. Nat Methods. 2018 Dec;15(12):994-996. doi: 10.1038/s41592-018-0224-7. PubMed PMID: 30504873; PubMed Central PMCID: PMC6518396.
  27. Yuan JT, Gatti DM, Philip VM, Kasparek S, Kreuzman AM, Mansky B, Sharif K, Taterra D, Taylor WM, Thomas M, Ward JO, Holmes A, Chesler EJ, Parker CC. Genome-wide association for testis weight in the diversity outbred mouse population. Mamm Genome. 2018 Jun;29(5-6):310-324. doi:10.1007/s00335-018-9745-8. Epub 2018 Apr 24. PubMed PMID: 29691636; PubMed Central PMCID: PMC6396879.
  28. Logan RW, Hasler BP, Forbes EE, Franzen PL, Torregrossa MM, Huang YH, Buysse DJ, Clark DB, McClung CA. Impact of Sleep and Circadian Rhythms on Addiction Vulnerability in Adolescents. Biol Psychiatry. 2018 Jun 15;83(12):987-996. doi: 10.1016/j.biopsych.2017.11.035. Epub 2017 Dec 15. Review. PubMed PMID: 29373120; PubMed Central PMCID: PMC5972052.
  29. DePoy LM, McClung CA, Logan RW. Neural Mechanisms of Circadian Regulation of Natural and Drug Reward. Neural Plast. 2017;2017:5720842. doi: 10.1155/2017/5720842. Epub 2017 Nov 21. Review. PubMed PMID: 29359051; PubMed Central PMCID: PMC5735684.
  30. Delprato A, Algéo MP, Bonheur B, Bubier JA, Lu L, Williams RW, Chesler EJ, Crusio WE. QTL and systems genetics analysis of mouse grooming and behavioral responses to novelty in an open field. Genes Brain Behav. 2017 Nov;16(8):790-799. doi: 10.1111/gbb.12392. Epub 2017 Jun 22. PubMed PMID: 28544613; PubMed Central PMCID: PMC5800503.
  31. Egervari G, Ciccocioppo R, Jentsch JD, Hurd YL. Shaping vulnerability to addiction - the contribution of behavior, neural circuits and molecular mechanisms. Neurosci Biobehav Rev. 2018 Feb;85:117-125. doi: 10.1016/j.neubiorev.2017.05.019. Epub 2017 May 29. Review. PubMed PMID: 28571877; PubMed Central PMCID: PMC5708151.
  32. Parker CC, Dickson PE, Philip VM, Thomas M, Chesler EJ. Systems Genetic Analysis in GeneNetwork.org. Curr Protoc Neurosci. 2017 Apr 10;79:8.39.1-8.39.20. doi: 10.1002/cpns.23. PubMed PMID: 28398643; PubMed Central PMCID: PMC5548442.