Selected Publications

• Ke, S.*, Anquetil, V.*, Rojas-Zamalloa J.*, Maity, A., Yang, A., Arias, M.A., Kalachikov, S., Ju, J. & Chasin L.A. Saturation mutagenesis reveals manifold determinants of exon definition, Genome Research 2018 10.1101/gr.219683.116 (* Joint-first author)

• Ke, S., Pandya-Jones, A., Saito, Y., Fak, J.J., Vagbo, C.B., Geula, S., Black, D.L., Darnell J.E. Jr. & Darnell R.B. m6A mRNA modifications are deposited in nascent pre-mRNA and are not required for splicing but do specify cytoplasmic turnover, Genes & Development 2017, 31: 990-1006.

• Ke, S., Alemu, E.A., Mertens, C., Gantman, E.C., Fak, J.J., Mele, A., Haripal, B., Zucker-Scharff, I., Moore, M.J., Park, C.Y., Vagbo, C.B., Kussnierczyk, A., Klungland, A., Darnell J.E. Jr. & Darnell R.B. A majority of m6A residues are in the last exons, allowing the potential for 3' UTR regulation, Genes & Development 2015, 29:2037-53.

• Ke, S., Shang, S., Kalachikov, S.M., Morozova, I., Yu, L., Russo, J.J., Ju, J. & Chasin, L.A. Quantitative evaluation of all hexamers as exonic splicing elements, Genome Research 2011, 21:1360-74.

• Ke, S., Chasin, L.A. Intronic motif pairs cooperate across exons to promote pre-mRNA splicing. Genome Biology 2010, 11:R84.