Kristen Onos, Ph.D.
Research Scientist
Studying how different genetic backgrounds and experience mediate disease onset, disease progression and resiliency.
Kristen Onos, PhD is a Research Scientist in the Howell lab. She is focused on improving preclinical to clinical translation of mouse models of neurodegeneration and drug testing. Her primary interests revolve around how changes in bioenergetics influence vascular function and glial activation. She is also an active member of the MODEL-AD consortium and a strong advocate for open science.
Grants, honors and accomplishments
July 2017 Selected as Maine Alfond Leader
May 2017 IBANGS Travel Award
September 2016 - current Nathan Shock Center of Excellence Project Pilot Award, National Institute on Aging
"Investigating the complex interactions between APOE and TREM2, the major genetic risk factors for Alzheimer's disease"
March 2014 - March 2016 T-32 Developmental Genetics Award
"Understanding cell-specific role of Bin1 in development, aging and Alzheimer's disease"
-
Research HighlightSeptember 20, 2022Collaborating to improve the lives of Alzheimer's patients
Kristen Onos is a key player in developing drug testing pipelines to determine outcomes of potential Alzheimer’s disease treatments and preventatives. -
Research HighlightFebruary 09, 2021Alzheimer’s disease, microglia and genetic diversity
Natural genetic variation determines microglia heterogeneity in wild-derived mouse models of Alzheimer’s disease.
-
Press ReleaseApril 13, 2021Alzheimers Association awards research grant to JAX scientists
The Alzheimer's Association awarded a grant to Jackson Laboratory researchers, Gareth Howell, Ph.D. and Kristen Onos, Ph.D., for their work deciphering microglial responses to amyloid and tau with wild-derived mice. -
Research HighlightJune 04, 2019Going wild: A better way to model Alzheimer's disease in mice
New research shows that wild-derived mouse strains show human-like variety in Alzheimer’s gene effects.