Structural variations including copy number variations (CNVs) in the human genome have been suggested to play important roles in human evolution, genetic diversity, disease susceptibility and pathogenesis. Our laboratory focuses on the development and application of state-of-the-art technologies to study the structure variations and functions of human genomes, and to understand the molecular mechanisms of human diseases.  In addition, we provide Clinical Cytogenetics and Molecular Genetics services and conduct translational research for precision medicine at our CLIA-certified Clinical Laboratory.