I envision my future research to investigate the roles of m6A modification in neurogenesis.
Zhiyuan received his Ph.D. degree at College of Life Science, Wuhan University. In Ph.D. training, his work was focused on regulation of Notch signaling and long-noncoding RNA. Currently, Zhiyuan is a Postdoctoral associate in Dr. Shengdong Ke’s Lab at The Jackson Laboratory. He envisions his research to investigate the roles of m6A modification in neurogenesis. How dysregulation of epitranscriptome contributes to brain disorders? What’s the mechanism of m6A signaling modulating the tempo of cortical neurogenesis? How does the cellular machinery target m6A to the correct transcripts? Answering these questions will advance the understanding of brain development and cell fate decision. Meanwhile, Zhiyuan is also interested in deep learning. He is devoted to develop a novel method to predict m6A sites and discover its biological significance.