Sarah Neuner

Ph.D. Student

My primary research interest is identifying how an individual's genetic makeup contributes to their susceptibility or resilience to disease, particularly Alzheimer's disease and dementia.

I joined the Kaczorowski lab as a graduate student in the summer of 2013. My current research focuses on identifying genetic factors involved in modifying susceptibility or resilience to both age-related cognitive decline and Alzheimer’s disease. Using a variety of behavioral assays and molecular techniques, I have monitored a panel of genetically diverse mice across the lifespan and have identified those strains that are either particularly susceptible or resilient to disease. Genetic mapping techniques enabled the identification of genomic regions involved in modifying this phenotype, and currently I am using a combination of approaches, including viral gene therapy and electrophysiology, to identify and validate specific genes in these regions involved in disease susceptibility. The goal of my research project is to identify those genes that may be targeted to delay disease onset, ultimately providing new therapeutic targets and insight into disease mechanisms.

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Education and experience

Education

University of Tennessee Health Science Center
PhD, Neuroscience
Advisor: Dr. Catherine Kaczorowski
2013 - present

Stockton University
BS, Biology (minor: Chemistry)
2009-2012

Experience

Graduate Research Assistant
University of Tennessee Health Science Center, 2013-2016
The Jackson Laboratory, 2016-present