Saman Zeeshan, Ph.D.

Postdoctoral Associate

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About Saman Zeeshan, Ph.D.

Dr. Zeeshan has a PhD in Bioinformatics and her research is aimed at understanding highly aggressive cancers. Associated with “The Cancer Isoform Program” in deciphering the basis of cancer with in-depth isoformic characterization of cancer cells leveraging modern genomic tools with the aim to develop novel therapeutic strategies for precision medicine. Her work is focused on transcriptome profiling of high-grade cancers such as triple negative breast cancer and melanoma that are characterized by a high level of genetic heterogeneity that are not responsive to targeted interventions.

As immuno-oncology takes center stage in the battle against cancer, the need for biomarkers has become even more acute. Applying immunoinformatics to studying cancer biology, her work has led her to identify alternative-splicing alterations in cancer and develop a quantitative, in-depth mechanistic understanding of molecular communication governing the dynamics of the tumorigenesis. Identification of novel signatures at various stages and with different treatments will serve as promising candidates for novel therapeutics as well as biomarkers for precise treatment and management.

Search MagazineJune 18, 2019
Connected through Science
When Isabelle Chen, a senior at The Ethel Walker School in Simsbury, Conn., met Ann Bresnahan ‘69 during a science alumnae panel discussion at Bresnahan’s 50-year high school reunion, the two knew that they shared a passion for science.
Featured ArticleJune 04, 2019
MCGI Advances clinical genomics education in Maine
Oncology practices in Maine will continue to have access to advanced educational curricula on genomic tumor testing in patient care through the Maine Cancer Genomics Initiative (MCGI), thanks to a gift from the Maine Cancer Foundation.
- Meet our donors
- Cancer
Search MagazineMay 22, 2019
JAX scientists speak out on the crisis of opioid addiction
JAX scientists are intensifying their efforts to shed light on the genetic and neurobiological causes of addiction, along with the impact of environmental influences.
Research HighlightMay 02, 2019
How can we take full advantage of EHR Data?
There has been an explosion of digital medical data in recent years, taking many forms. Much of the most valuable data—clinical patient data—is currently stored in electronic health record (EHR) systems, providing a theoretical gold mine for large-scale integration and analyses of patient traits, diseases, treatments, progression over time, outcomes and more.

Tech CornerJune 17, 2019
The genome of Eve (the mouse)
C57BL/6—aka Black 6—is the most widely used mouse strain in research. Its reference genome was published in 2003 and has been carefully curated over the years since.
Featured ArticleMay 29, 2019
Making a community impact beyond the bench
A JAX postdoctoral associate was recently awarded a fellowship in Science Policy from the Society for Industrial and Applied Mathematics that will allow him to advocate for support of science research with federal officials and congressional staff.
Research HighlightMay 20, 2019
Revealing cellular traits, one cell at a time
Scientists have developed an expanded toolkit that enables investigations of cellular traits at the single cell level at an unprecedented level of detail.
Featured ArticleApril 30, 2019
Mapping a Cancer Free Life
Jens Rueter, Medical Director of the Maine Cancer Genomics Initiative, and Madeleine Braun, Chief of Presidential Initiatives at JAX, discuss the future of cancer care during the first 2019 JAXtaposition event at the Portland Museum of Art.