Huawen Li, Ph.D.

Postdoctoral Associate

Conducts research seeking targets for new pharmaceutical approaches based on protein stress.

About Huawen Li, Ph.D.

The stress response is an evolutionarily, highly conserved adaptive mechanism that enhances cell survival. Genome instability is a hallmark of cancer cells. We are highly interested in the relationship between these two factors. We use mouse models to mimic lung cancer, which have obvious genome instability. We also use molecular methods to find the basis for how these pathways talk to each other. This work might give us some clue or target for new pharmaceutical approaches based on protein stress.

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Research HighlightJune 21, 2018
Finding the genes controlling ovarian reserve could hold key to better female fertility care
Jackson Laboratory Assistant Professor Ewelina Bolcun-Filas, Ph.D., is looking at how multiple genetic factors regulating oocyte development determine the differences in each woman’s ovarian reserve.
Tech CornerMay 04, 2018
What's new in cancer research?
The field of cancer immunotherapy research is extremely exciting, yet still somewhat mysterious, as researchers grapple with the fine-tuning of patient response.
- Cancer/Tumors
- Cancer
Press ReleaseApril 23, 2018
The role of extra DNA in cancer evolution and therapy resistance
New research is providing a better understanding of the processes underlying cell-to-cell differences within glioblastoma tumors — a crucial finding because these differences contribute to therapy resistance.
- Cancer/Tumors
- Cancer
Tech CornerApril 10, 2018
Cancer and its immune environment bioprinted and reproduced live and in 3D
New 3D bioprinting technique creates a platform for precision immunotherapy study.

Research HighlightJune 11, 2018
Measuring tumor heterogeneity for better, evolution-based cancer treatment strategies
JAX Associate Professor Jeffrey Chuang, Ph.D., has been awarded a five-year grant totaling $2,650,484 from the National Cancer Institute for research that could pave the way for the first evolution-based approaches to cancer treatment.
- Cancer/Tumors
- Cancer
Search MagazineApril 27, 2018
Finding precise cures for cancer
At JAX's new speaker event series, JAXtaposition, two scientific leaders shared how the Maine Cancer Genomics Initiative and JAX’s cutting-edge genomic testing is giving physicians access to the most advanced precision cancer care for their patients.
- Cancer/Tumors
- Cancer
Research HighlightApril 10, 2018
Cancer research: Beyond the Petri dish
The latest developments in cancer research and their translation to oncology practice offer truly exciting potential for better therapies in the near future.
Press ReleaseApril 05, 2018
PDX Finder — Free global portal for cancer models
First global online catalog of Patient-Derived Xenograft models helps cancer researchers save valuable time.