Huawen Li, Ph.D.

Postdoctoral Associate

Conducts research seeking targets for new pharmaceutical approaches based on protein stress.

About Huawen Li, Ph.D.

The stress response is an evolutionarily, highly conserved adaptive mechanism that enhances cell survival. Genome instability is a hallmark of cancer cells. We are highly interested in the relationship between these two factors. We use mouse models to mimic lung cancer, which have obvious genome instability. We also use molecular methods to find the basis for how these pathways talk to each other. This work might give us some clue or target for new pharmaceutical approaches based on protein stress.

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Press ReleaseAugust 01, 2018
A RACIPE for success
New five-year, $2.2M outstanding investigator grant to Mingyang Lu will support systems biology algorithm approach.
Research HighlightJuly 12, 2018
The distinct forms of an important genomic disruption
A new paper further explains the genomic disruption known as the tandem duplicator phenotype (TDP), a common attribute in some of the most deadly cancers of women.
Research HighlightJune 21, 2018
Finding the genes controlling ovarian reserve could hold key to better female fertility care
Jackson Laboratory Assistant Professor Ewelina Bolcun-Filas, Ph.D., is looking at how multiple genetic factors regulating oocyte development determine the differences in each woman’s ovarian reserve.
Tech CornerMay 04, 2018
What's new in cancer research?
The field of cancer immunotherapy research is extremely exciting, yet still somewhat mysterious, as researchers grapple with the fine-tuning of patient response.
- Cancer/Tumors
- Cancer

Research HighlightJuly 30, 2018
Immune system 2.0: Can we re-engineer the human immune response?
JAX researchers have demonstrated the ability to target and disrupt specific genes and/or alter their expression levels, which has important implications for both immunology research and clinical treatments.
Research HighlightJune 28, 2018
How do cancer cells achieve immortality?
Cancer cell immortality leads to massive tumors, metastatic spread, and potentially re-emergence. Researchers are working to determine how cancer cells achieve immortality.
- Cancer/Tumors
- Cancer
Research HighlightJune 11, 2018
Measuring tumor heterogeneity for better, evolution-based cancer treatment strategies
JAX Associate Professor Jeffrey Chuang, Ph.D., has been awarded a five-year grant totaling $2,650,484 from the National Cancer Institute for research that could pave the way for the first evolution-based approaches to cancer treatment.
- Cancer/Tumors
- Cancer
Search MagazineApril 27, 2018
Finding precise cures for cancer
At JAX's new speaker event series, JAXtaposition, two scientific leaders shared how the Maine Cancer Genomics Initiative and JAX’s cutting-edge genomic testing is giving physicians access to the most advanced precision cancer care for their patients.
- Cancer/Tumors
- Cancer