Novel Models Developed for Type 1 Diabetes Target Validation Studies
Whether you already have gene-targeted ES cells, a DNA construct or need a completely custom model, you can leverage JAX's experience with genetic engineering technologies to generate the models you need on the most relevant background for your research.
Our custom model generation service enables the generation of various mouse models including, knock-ins, knockouts, conditional knockouts, point mutations, and genetically humanized models.
To create your large targeted genomic mutation, our ES cell microinjection service will utilize traditional techniques to successfully take you from a modified ES cell clone to a new strain in a matter of weeks.
Express your gene of interest in the inbred background of your choice using our DNA microinjection services.
In Vivo Pharmacology Services at JAX performs contract efficacy studies using NOD/ShiLtJ (001976) mice to evaluate new Type 1 diabetes-related therapeutics.
Need dozens or hundreds of age-matched mice fast? Speed expansion via IVF rapidly develops mouse colonies at a specified and opportunistic pathogen-free status.
Protect your valuable strains from unfortunate events. JAX Cryopreservation Services offer fast and reliable recovery of archived embryos and sperm so you can feel assured about the safety of your strains.