CRISPR/Cas Limited Use License Terms with the Broad Institute

The creation of your mouse strain (the Licensed Product) is sold by The Jackson Laboratory (Jackson) under a license agreement with the Broad Institute, Inc. (Broad) that contains certain limitations and obligations. By purchasing this product, you (the Limited Licensee) agree to be bound by the following limited license (the Limited License). Additional capitalized terms are defined below.

Limited Licensee is granted the non-transferable right to use the Licensed Product and Enabled Products purchased from Jackson solely for research conducted by such Limited Licensee in accordance with all of the following requirements: (i) the Limited Licensee shall not sell or otherwise transfer the Licensed Product or Enabled Products (including without limitation any material that contains the Licensed Product or Enabled Products in whole or part) to any other person or entity or use the Licensed Product or Enabled Products to perform services for the benefit of any other person or entity other than bona fide research collaborators or contract research organizations, (ii) the Limited Licensee shall use only the purchased amount of the Licensed Product and components of the Licensed Product and Enabled Products, only for its internal research within the Field and not for any Commercial Purposes, however the Limited License will not prevent breeding of the Licensed Product for use under the Limited License, (iii) the Limited Licensee shall use the Licensed Product and Enabled Products in compliance with all applicable laws and regulations, including without limitation applicable human health and animal welfare laws and regulations, (iv) Jackson, Broad, The Massachusetts Institute of Technology (MIT) and the President and Fellows of Harvard College (Harvard) provide no warranties of any kind to the Limited Licensee (statutory or implied) concerning the Patent Rights, the Licensed Product or Enabled Products, including without limitation, as to product quality, condition, description, merchantability, fitness for a particular purpose, non-infringement of intellectual property rights or the absence of latent or other defects, and all such warranties are hereby expressly disclaimed, (v) Jackson, Broad, MIT and Harvard expressly disclaim any warranty regarding results obtained through the use of the Licensed Product or Enabled Products, including without limitation any claim of inaccurate, invalid or incomplete results, (vi) Jackson, Broad, MIT and Harvard, and their current and former directors, trustees, officers, employees, agents, faculty, affiliated investigators, and students, and their respective successors, heirs and assigns (collectively, the Indemnitees) shall have no liability to the Limited Licensee, including, without limitation, for any loss of use or profits, business interruption or any consequential, incidental, special or other indirect damages of any kind, regardless of how caused and regardless of whether an action in contract, tort, strict product liability or otherwise, (vii) the Limited Licensee shall indemnify, defend and hold harmless the Indemnitees against any liability, damage, loss, or expense (including without limitation reasonable attorneys fees and expenses) incurred by or imposed upon any of the Indemnitees in connection with any claims, suits, investigations, actions, demands or judgments arising out of or related to the exercise of any rights granted to the Limited Licensee under the Limited License or any breach of the Limited License by such Limited Licensee, provided, however, that the foregoing shall not apply to a Limited Licensee that is an academic, non-profit, or government entity or person, and such Limited Licensee instead agrees that it, and not the Indemnitees, shall be responsible for any liability, damage, loss or expense arising out of or related to the exercise of any rights grant to the Limited Licensee under the Limited License or any breach of the Limited License by the Limited Licensee, and (viii) the Licensed Product and its use may be the subject of one or more issued patents and/or pending patent applications owned by Jackson, Broad, MIT and Harvard and the purchase of the Licensed Product does not convey a license under any claims in the foregoing patents or patent applications directed to the Licensed Product or use, production or commercialization thereof, other than the right to use the Licensed Product under the Limited License set forth above or as otherwise agreed between the parties in writing.

Definitions:

Commercial Purpose means: (a) the practice, performance or provision of any method, process or service, or (b) the manufacture, sale, use, distribution, disposition or importing of any product, in each case (a) or (b) for consideration, e.g., a fee, or on any other commercial basis.

Enabled Product means: any product, that is not the Licensed Product, which is or incorporates (a) any progeny, modification or derivative of the Licensed Product, or (b) any cell, organism or animal made or modified through use of the Licensed Product, or any progeny, modification or derivative of such cell, organism or animal. For clarity, any product that is made, produced or derived by use of the technology of the Patent Rights, such as a protein or a peptide from a cell line shall be deemed an Enabled Product; provided, however, that the term Enabled Product shall not include any large or small molecule that (i) was identified or discovered through screening using technology covered by the Patent Rights and (ii) does not otherwise fall within the foregoing clauses (a) through (b).

Field means: use as a research tool for research purposes; provided, however, that notwithstanding the foregoing, the Field shall expressly exclude (a) any clinical use, including, without limitation, diagnostic and prognostic use, (b) any human, veterinary, livestock or agricultural use, or (c) the manufacture, distribution, importation, exportation, transportation, sale, offer for sale, marketing, promotion or other exploitation or use of, or as, a testing service, therapeutic or diagnostic for humans or animals.

Patent Rights means (a) any patents and patent applications listed on Appendix A, which shall be updated from time-time.; (b) any substitutions, divisions, continuations, reissues, renewals, re-examinations or extensions of any patents or patent applications of (a), any continuations-in-part of any patents or patent applications of (a) to the extent the claims are directed to subject matter specifically described in a patent or patent application set forth on Appendix A, and any application claiming priority to a provisional application set forth on Appendix A to the extent the claims are directed to subject matter specifically described in a provisional patent application set forth on Appendix A; (c) any letters patents and/or the equivalent issuing therefrom in any jurisdiction based on any of the foregoing, and (d) any foreign or international equivalents of any of the foregoing, including without limitation any applications filed under the Patent Cooperation Treaty.

Appendix A.

Case Number Broad Ref# App Number File Date App Title

44790.AA.2003

BI-2011/008.PA1

61/736,527

12-Dec-12

SYSTEMS METHODS AND COMPOSITIONS FOR SEQUENCE MANIPULATION

44790.BB.2003

BI-2011/008.PA2

61/748,427

2-Jan-13

SYSTEMS METHODS AND COMPOSITIONS FOR SEQUENCE MANIPULATION

44790.00.2003

BI-2011/008.PA3

61/757,972

29-Jan-13

SYSTEMS METHODS AND COMPOSITIONS FOR SEQUENCE MANIPULATION

44790.01.2003

BI-2011/008.PA4

61/768,959

25-Feb-13

SYSTEMS METHODS AND COMPOSITIONS FOR SEQUENCE MANIPULATION

44790.02.2003

BI-2011/008.PA5

61/791,409

15-Mar-13

SYSTEMS METHODS AND COMPOSITIONS FOR SEQUENCE MANIPULATION

44790.03.2003

BI-2011/008.PA6

61/835,931

17-Jun-13

SYSTEMS METHODS AND COMPOSITION FOR SEQUENCE MANIPULATION

44790.07.2003

BI-2011/008.US1

14/105,035

12-Dec-13

CRISPR-CAS COMPONENT SYSTEMS, METHODS AND COMPOSITIONS FOR SEQUENCE MANIPULATION 

44790.99.2003

BI-2011/008.WO1

PCT/US2013/074611

12-Dec-13

CRISPR-CAS COMPONENT SYSTEMS, METHODS AND COMPOSITIONS FOR SEQUENCE MANIPULATION 

44790.80.2003

BI-2011/008.EP1

13812430

29-Sep-14

CRISPR-CAS COMPONENT SYSTEMS, METHODS AND COMPOSITIONS FOR SEQUENCE MANIPULATION

44790.80.2044

BI-2011/008A.EP1

13824232.6

2-May-14

CRISPR-CAS SYSTEMS AND METHODS FOR ALTERING EXPRESSION OF GENE PRODUCTS

44790.04.2003

BI-2011/008A.US1

61/842,322

2-Jul-13

CRISPR-CAS SYSTEMS AND METHODS FOR ALTERING EXPRESSION OF GENE PRODUCTS

44790.05.2003

BI-2011/008A.US2

14/054,414

15-Oct-13

CRISPR-CAS SYSTEMS AND METHODS FOR ALTERING EXPRESSION OF GENE PRODUCTS (USP 8,697,359, issued April 15, 2014)

44790.11.2003

BI-2011/008A.US3

14/183,429

18-Feb-14

CRISPR-CAS SYSTEMS AND METHODS FOR ALTERING EXPRESSION OF GENE PRODUCTS (USP 8,771,945, issued July 8, 2014)

44790.10.2003

BI-2011/008A.US4

14/183,486

18-Feb-14

CRISPR-CAS COMPONENT SYSTEMS, METHODS AND COMPOSITIONS FOR SEQUENCE MANIPULATION (USP 8,795,965, issued August 5, 2014)

44790.13.2003

BI-2011/008A.US5

14/256,912

18-Apr-14

CRISPR-CAS SYSTEMS AND METHODS FOR ALTERING EXPRESSION OF GENE PRODUCTS

44790.14.2003

BI-2011/008A.US6

14/497,627

26-Sep-14

CRISPR-CAS COMPONENT SYSTEMS, METHODS AND COMPOSITIONS FOR SEQUENCE MANIPULATION

44790.99.2044

BI-2011/008A.WO1

PCT/US2013/074743

12-Dec-13

CRISPR-CAS SYSTEMS AND METHODS FOR ALTERING EXPRESSION OF GENE PRODUCTS

44790.06.2003

BI-2011/008B.US1

14/105,031

12-Dec-13

CRISPR-CAS NICKASE SYSTEMS, METHODS AND COMPOSITIONS FOR SEQUENCE MANIPULATION IN EUKARYOTES

44790.08.2003

BI-2011/008B.US2

14/183,471

18-Feb-14

CRISPR-CAS NICKASE SYSTEMS, METHODS AND COMPOSITIONS FOR SEQUENCE MANIPULATION IN EUKARYOTES (USP 8,889,356 to be issued November 18, 2014)

44790.09.2003

BI-2011/008B.US3

14/258,458

22-Apr-14

CRISPR-CAS COMPONENT SYSTEMS, METHODS AND COMPOSITIONS FOR SEQUENCE MANIPULATION 

44790.12.2003

BI-2011/008B.US4

14/259,420

23-Apr-14

CRISPR-CAS COMPONENT SYSTEMS, METHODS AND COMPOSITIONS FOR SEQUENCE MANIPULATION (USP 8,871,445, issued October 28, 2014)

44790.99.2045

BI-2011/008B.WO1

PCT/US2013/074790

12-Dec-13

CRISPR-CAS NICKASE SYSTEMS, METHODS AND COMPOSITIONS FOR SEQUENCE MANIPULATION IN EUKARYOTES 

44790.00.2005

BI-2011/020.PA1

61/675,778

25-Jul-12

INDUCIBLE DNA BINDING PROTEINS AND GENOME PERTURBATION TOOLS AND APPLICATIONS THEREOF

44790.01.2005

BI-2011/020.PA2

61/721,283

1-Nov-12

INDUCIBLE DNA BINDING PROTEINS AND GENOME PERTURBATION TOOLS AND APPLICATIONS THEREOF

44790.02.2005

BI-2011/020.PA3

61/736,465

12-Dec-12

INDUCIBLE DNA BINDING PROTEINS AND GENOME PERTURBATION TOOLS AND APPLICATIONS THEREOF

44790.03.2005

BI-2011/020.PA4

61/794,458

15-Mar-13

INDUCIBLE DNA BINDING PROTEINS AND GENOME PERTURBATION TOOLS AND APPLICATIONS THEREOF

44790.12.2022

BI-2011/020.PA5

61/835,973

17-Jun-13

INDUCIBLE DNA BINDING PROTEINS AND GENOME PERTURBATION TOOLS AND APPLICATIONS THEREOF

44790.99.2005

BI-2011/020.WO1

PCT/US13/051418

21-Jul-13

INDUCIBLE DNA BINDING PROTEINS AND GENOME PERTURBATION TOOLS AND APPLICATIONS THEREOF

44790.11.2022

BI-2012/084.PA1

61/836,080

17-Jun-13

METHODS, SYSTEMS, AND APPARATUS FOR IDENTIFYING TARGET SEQUENCES FOR CAS ENZYMES OR CRISPR-CAS SYSTEMS FOR TARGET SEQUENCES AND CONVEYING RESULTS THEREOF

44790.00.2040

BI-2012/084A.US1

14/104,900

12-Dec-13

METHODS, SYSTEMS, AND APPARATUS FOR IDENTIFYING TARGET SEQUENCES FOR CAS ENZYMES OR CRISPR-CAS SYSTEMS FOR TARGET SEQUENCES AND CONVEYING RESULTS THEREOF

44790.99.2040

BI-2012/084A.WO1

PCT/US2013/074825

12-Dec-13

METHODS, SYSTEMS, AND APPARATUS FOR IDENTIFYING TARGET SEQUENCES FOR CAS ENZYMES OR CRISPR-CAS SYSTEMS FOR TARGET SEQUENCES AND CONVEYING RESULTS THEREOF

44790.99.2046

BI-2012/084B.WO1

PCT/US2013/074812

12-Dec-13

METHODS, MODELS, SYSTEMS, AND APPARATUS FOR IDENTIFYING TARGET SEQUENCES FOR CAS ENZYMES FOR CRISPR-CAS SYSTEMS FOR TARGET SEQUENCES AND CONVEYING RESULTS THEREOF

44790.00.2041

BI-2013/003.US1

14/104,837

12-Dec-13

DELIVERY, ENGINEERING AND OPTIMIZATION OF SYSTEMS, METHODS AND COMPOSITIONS FOR SEQUENCE MANIPULATION AND THERAPEUTIC APPLICATIONS

44790.01.2041

BI-2013/003.US2

14/183,512

18-Feb-14

DELIVERY, ENGINEERING AND OPTIMIZATION OF SYSTEMS, METHODS AND COMPOSITIONS FOR SEQUENCE MANIPULATION AND THERAPEUTIC APPLICATIONS

44790.02.2041

BI-2013/003.US3

14/481,339

9-Sep-14

DELIVERY, ENGINEERING, AND OPTIMIZATION OF SYSTEMS, METHODS AND COMPOSITIONS FOR SEQUENCE MANIPULATION AND THERAPEUTIC APPLICATIONS

44790.99.2041

BI-2013/003.WO1

PCT/US2013/074667

12-Dec-13

DELIVERY, ENGINEERING, AND OPTIMIZATION OF SYSTEMS, METHODS AND COMPOSITIONS FOR SEQUENCE MANIPULATION AND THERAPEUTIC APPLICATIONS

44790.00.2022

BI-2013/003/004.PA1

61/758,468

30-Jan-13

ENGINEERING AND OPTIMIZATION OF SYSTEMS, METHODS AND COMPOSITIONS FOR SEQUENCE MANIPULATION

44790.01.2022

BI-2013/003/004.PA2

61/769,046

25-Feb-13

ENGINEERING AND OPTIMIZATION OF SYSTEMS, METHODS AND COMPOSITIONS FOR SEQUENCE MANIPULATION

44790.02.2022

BI-2013/003/004.PA3

61/802,174

15-Mar-13

ENGINEERING AND OPTIMIZATION OF SYSTEMS, METHODS AND COMPOSITIONS FOR SEQUENCE MANIPULATION

44790.03.2022

BI-2013/003/004.PA4

61/806,375

28-Mar-13

ENGINEERING AND OPTIMIZATION OF SYSTEMS, METHODS AND COMPOSITIONS FOR SEQUENCE MANIPULATION

44790.04.2022

BI-2013/003/004.PA5

61/814,263

20-Apr-13

ENGINEERING AND OPTIMIZATION OF SYSTEMS, METHODS AND COMPOSITIONS FOR SEQUENCE MANIPULATION

44790.05.2022

BI-2013/003/004.PA6

61/819,803

6-May-13

ENGINEERING AND OPTIMIZATION OF SYSTEMS, METHODS AND COMPOSITIONS FOR SEQUENCE MANIPULATION

44790.06.2022

BI-2013/003/004.PA7

61/828,130

28-May-13

ENGINEERING AND OPTIMIZATION OF SYSTEMS, METHODS AND COMPOSITIONS FOR SEQUENCE MANIPULATION

44790.10.2022

BI-2013/003D.PA1

61/836,123

17-Jun-13

DELIVERY, ENGINEERING AND OPTIMIZATION OF SYSTEMS, METHODS AND COMPOSITIONS FOR SEQUENCE MANIPULATION AND APPLICATIONS

44790.13.2022

BI-2013/003D.PA2

61/847,537

17-Jul-13

DELIVERY, ENGINEERING AND OPTIMIZATION OF SYSTEMS, METHODS AND COMPOSITIONS FOR SEQUENCE MANIPULATION AND APPLICATIONS

44790.14.2022

BI-2013/003D.PA3

61/862,355

5-Aug-13

DELIVERY, ENGINEERING AND OPTIMIZATION OF SYSTEMS, METHODS AND COMPOSITIONS FOR SEQUENCE MANIPULATION AND APPLICATIONS

44790.15.2022

BI-2013/003D.PA4

61/871,301

28-Aug-13

DELIVERY, ENGINEERING AND OPTIMIZATION OF SYSTEMS, METHODS AND COMPOSITIONS FOR SEQUENCE MANIPULATION AND APPLICATIONS

44790.16.2022

BI-2013/003D.PA5

61/915,383

12-Dec-13

OPTIMIZED CRISPR-CAS DOUBLE NICKASE SYSTEMS, METHODS AND COMPOSITIONS FOR SEQUENCE MANIPULATION

44790.99.2022

BI-2013/003D.WO1

PCT/US2014/041803

10-Jun-14

OPTIMIZED CRISPR-CAS DOUBLE NICKASE SYSTEMS, METHODS AND COMPOSITIONS FOR SEQUENCE MANIPULATION

44790.09.2022

BI-2013/004E.PA1

61/836,101

17-Jun-13

ENGINEERING AND OPTIMIZATION OF IMPROVED SYSTEMS, METHODS AND ENZYME COMPOSITIONS FOR SEQUENCE MANIPULATION

44790.00.2042

BI-2013/004E.US1

14/104,977

12-Dec-13

ENGINEERING AND OPTIMIZATION OF IMPROVED SYSTEMS, METHODS AND ENZYME COMPOSITIONS FOR SEQUENCE MANIPULATION

44790.01.2042

BI-2013/004E.US2

14/222,930

24-Mar-14

ENGINEERING AND OPTIMIZATION OF IMPROVED SYSTEMS, METHODS AND ENZYME COMPOSITIONS FOR SEQUENCE MANIPULATION (USP 8,865,406, issued October 21, 2014)

44790.02.2042

BI-2013/004E.US3

14/293,498

2-Jun-14

ENGINEERING AND OPTIMIZATION OF IMPROVED SYSTEMS, METHODS AND ENZYME COMPOSITIONS FOR SEQUENCE MANIPULATION

44790.03.2042

BI-2013/004E.US4

14/293,674

2-Jun-14

ENGINEERING AND OPTIMIZATION OF IMPROVED SYSTEMS, METHODS AND ENZYME COMPOSITIONS FOR SEQUENCE MANIPULATION (USP8,889,418, to be issued November 18, 2014)

44790.99.2042

BI-2013/004E.WO1

PCT/US2013/074691

12-Dec-13

ENGINEERING AND OPTIMIZATION OF IMPROVED SYSTEMS, METHODS AND ENZYME COMPOSITIONS FOR SEQUENCE MANIPULATION

44790.07.2022

BI-2013/004F.PA1

61/835,936

17-Jun-13

ENGINEERING AND OPTIMIZATION OF SYSTEMS, METHODS AND COMPOSITIONS FOR SEQUENCE MANIPULATION WITH FUNCTIONAL DOMAINS

44790.00.2043

BI-2013/004F.US1

14/105,017

12-Dec-13

ENGINEERING AND OPTIMIZATION OF SYSTEMS, METHODS AND COMPOSITIONS FOR SEQUENCE MANIPULATION WITH FUNCTIONAL DOMAINS 

44790.01.2043

BI-2013/004F.US2

14/226,274

26-Mar-14

ENGINEERING AND OPTIMIZATION OF SYSTEMS, METHODS AND COMPOSITIONS FOR SEQUENCE MANIPULATION WITH FUNCTIONAL DOMAINS

44790.99.2043

BI-2013/004F.WO1

PCT/US2013/074736

12-Dec-13

ENGINEERING AND OPTIMIZATION OF SYSTEMS, METHODS AND COMPOSITIONS FOR SEQUENCE MANIPULATION WITH FUNCTIONAL DOMAINS 

44790.80.2047

BI-2013/004G.EP1

13818570.7

27-May-14

ENGINEERING OF SYSTEMS, METHODS AND OPTIMIZED GUIDE COMPOSITIONS FOR SEQUENCE MANIPULATION 

44790.80.2075

BI-2013/004G.EP2

14170383.5

28-May-14

ENGINEERING OF SYSTEMS, METHODS AND OPTIMIZED GUIDE COMPOSITIONS FOR SEQUENCE MANIPULATION

44790.08.2022

BI-2013/004G.PA1

61/836,127

17-Jun-13

ENGINEERING OF SYSTEMS, METHODS AND OPTIMIZED COMPOSITIONS FOR SEQUENCE MANIPULATION

44790.00.2047

BI-2013/004G.US1

14/104,990

12-Dec-13

ENGINEERING OF SYSTEMS, METHODS AND OPTIMIZED GUIDE COMPOSITIONS FOR SEQUENCE MANIPULATION

44790.01.2047

BI-2013/004G.US2

14/290,575

29-May-14

ENGINEERING OF SYSTEMS, METHODS AND OPTIMIZED GUIDE COMPOSITIONS FOR SEQUENCE MANIPULATION

44790.99.2047

BI-2013/004G.WO1

PCT/US2013/074819

12-Dec-13

ENGINEERING OF SYSTEMS, METHODS AND OPTIMIZED GUIDE COMPOSITIONS FOR SEQUENCE MANIPULATION

44790.00.2024

BI-2013/007.PA1

61/799,800

15-Mar-13

RECOMBINANT VIRUS AND PREPARATIONS THEREOF

44790.01.2024

BI-2013/007.US1

14/213,991

14-Mar-14

RECOMBINANT VIRUS AND PREPARATIONS THEREOF

44790.99.2024

BI-2013/007.WO1

PCT/US2014/30394

17-Mar-14

RECOMBINANT VIRUS AND PREPARATIONS THEREOF

44790.00.2034

BI-2013/066.PA1

61/862,468

5-Aug-13

DELIVERY, ENGINEERING AND OPTIMIZATION OF SYSTEMS, METHODS AND OPTIMIZED COMPOSITIONS FOR SEQUENCE MANIPULATION

44790.01.2034

BI-2013/066.PA2

61/915,407

12-Dec-13

DELIVERY, ENGINEERING AND OPTIMIZATION OF TANDEM GUIDE SYSTEMS, METHODS AND COMPOSITIONS FOR SEQUENCE MANIPULATION

44790.02.2034

BI-2013/066.PA3

61/979,942

15-Apr-14

DELIVERY, ENGINEERING AND OPTIMIZATION OF TANDEM GUIDE SYSTEMS, METHODS AND COMPOSITIONS FOR SEQUENCE MANIPULATION

44790.99.2034

BI-2013/066.WO1

PCT/US2014/041800

10-Jun-14

DELIVERY, ENGINEERING AND OPTIMIZATION OF TANDEM GUIDE SYSTEMS, METHODS AND COMPOSITIONS FOR SEQUENCE MANIPULATION

44790.00.2035

BI-2013/073.PA1

61/960,777

25-Sep-13

FUNCTIONAL GENOMICS USING CRISPR-CAS SYSTEMS, COMPOSITIONS, METHODS, SCREENS AND APPLICATIONS THEREOF

44790.03.2035

BI-2013/073.PA2

61/995,636

15-Apr-14

FUNCTIONAL GENOMICS USING CRISPR-CAS SYSTEMS, COMPOSITIONS, METHODS, SCREENS AND APPLICATIONS THEREOF

44790.99.2035

BI-2013/073.WO1

PCT/US2014/041806

10-Jun-14

FUNCTIONAL GENOMICS USING CRISPR-CAS SYSTEMS, COMPOSITIONS, METHODS, SCREENS AND APPLICATIONS THEREOF

44790.01.2035

BI-2013/073/078.PA1

61/961,980

28-Oct-13

FUNCTIONAL GENOMICS USING CRISPR-CAS SYSTEMS, COMPOSITIONS, METHODS, SCREENS AND APPLICATIONS THEREOF

44790.00.2065

BI-2013/112.US1

14/463,253

19-Aug-14

FUNCTIONAL GENOMICS USING CRISPR-CAS SYSTEMS, COMPOSITIONS, METHODS, KNOCKOUT LIBRARIES AND APPLICATIONS THEREOF

44790.99.2065

BI-2013/112.WO1

PCT/US2013/074800

12-Dec-13

FUNCTIONAL GENOMICS USING CRISPR-CAS SYSTEMS, COMPOSITIONS, METHODS, KNOCKOUT LIBRARIES AND APPLICATIONS THEREOF

44790.02.2041

BI-2014/071

14/481,339

9-Sep-14

DELIVERY ENGINEERING, AND OPTIMIZATION OF
SYSTEMS, METHODS AND COMPOSITIONS FOR SEQUENCE
MANIPULATION AND THERAPEUTIC APPLICATIONS

Last updated: November 17, 2014