Amyotrophic Lateral Sclerosis

Amyotrophic Lateral Sclerosis (ALS) or Lou Gehrig’s disease is a devastating and rapidly fatal disease with currently only one available, FDA-approved, modestly effective treatment. This disease is marked by progressive neurodegeneration of nerve cells in the brain and spinal cord that lead to loss of voluntary muscle movement.

As you work toward developing and testing therapeutics for your ALS research, we are here to help. From helping you select the ideal mouse model to performing your preclinical in vivo studies.

Efficacy studies performed by JAX In Vivo Services for ALS typically feature clinical observations, body weights, progressive neurological scoring, electrophysiological assessment of motor neuropathy, survival, tissue/blood collection and histological assessment of neuromuscular junctions and femoral nerves.