DIO Diet Composition

  • Inventoried C57BL/6J DIO mice are maintained on D12492 (60 kcal% fat) and the control diet, D12450B (10 kcal% fat) (Research Diets, Inc.)
  • Customized diets and studies can be designed for C57BL/6J or any other strain

Table 1. Macro-nutrient composition of lard-based high fat inventory DIO diets from Research Diets, Inc.

10 kcal% fat
(inventoried control)
D12450B

60 kcal% fat
(inventoried experimental)
D12492

 gm%
kcal%
gm%
kcal%
Protein
19

20

26

20

Carbohydrate
67

70

26

20

Fat

4

10

35

60

Total 
 

100

 

100

kcal/gm

3.8

 

5.2

 

 

gm
kcal
gm
kcal
Fat from lard

20

180

245

2205


Table 2. Macro-nutrient composition of hydrogenated coconut oil w/sucrose diets from Research Diets, Inc. (custom diets available upon request).

11 kcal% fat
(custom control)
D12329

58 kcal% fat
(custom experimental)
D12331

 gm%
kcal%
gm%
kcal%
Protein
17

16

23

16

Carbohydrate
74

73

36

26

Fat

5

11

36

58

Total 
 

100

 

100

kcal/gm

4.1

 

5.6

 

 

gm
kcal
gm
kcal
Sucrose

20

180

245

2205

 
Fat from coconut oil

40

 360

334 

3002