JAX BLOG: The Versatile Mouse Model for Rare Disease Research
Learn about mouse models in rare disease gene discovery and validation, and assessing safety and efficacy using mouse models.
Learn more about how JAX is enabling you to unravel
the pathway of your neurobiological research, including
our comprehensive mouse model catalog, knowledgeable study
directors to help you define your readouts, and wide range of
preclinical efficacy studies.
|210.09. Cross-species analyses identify Dlgap2 as a mediator of age-related cognitive decline and Alzheimer's disease||S. M. NEUNER, L. DUMITRESCU, L. ANDERSON, D. M. GATTI, A. R. OUELLETTE, E. MAHONY, J. A. BUBIER, G. CHURCHILL, L. PETERS, H.-S. YANG, C. REITZ, B. KUNKLE, C. C. WHITE, P. L. DE JAGER, J. A. SCHNEIDER, D. A. BENNETT, E. J. CHESLER, T. J. HOHMAN, C. C. KACZOROWSKI;||Poster: 210 - Alzheimer's Disease: Genetics|
|473.01. Lifespan magnetic resonance imaging of novel mouse models of Alzheimer's disease: Phenotyping and comparisons to healthy aging||A. JULLIENNE, A. OBENAUS, J. LEE, J. I. SZU, E. J. BEHRINGER, M. AD CONSORTIUM||Poster: 473 - Alzheimer's Disease and Other Dementias: Therapeutic Strategies II|
|473.03. Characterization and deep phenotyping of the 5xfAD mouse model by MODEL-AD
||S. FORNER, M. AD CONSORTIUM||Poster: 473 - Alzheimer's Disease and Other Dementias: Therapeutic Strategies II|
|473.07. Comparative transcriptome analysis of MODEL-AD mouse models||G. BALDERRAMA-GUTIERREZ, A. MORTAZAVI, M. AD CONSORTIUM||Poster: 473 - Alzheimer's Disease and Other Dementias: Therapeutic Strategies II|
|566.13. CHCHD10 a protein at the intersection of mitochondrial diseases and ALS-FTD||H. KAWAMATA, C. J. ANDERSON, K. BREDVIK, S. M. MEADOWS, C. M. LUTZ, G. MANFREDI5||Poster: 566 - Neurodegeneration Mechanisms|
|591.11. Elevated dietary sucrose consumption induces AgRP neuronal circuit dysregulation and leptin resistance without altering body weight||A. C. KORGAN, K. ABREU, K. GRAHAM, W. WEI, S. L. A. MARTIN, K. M. S. O'CONNELL;||Poster: 591 - Food Intake and Energy Balance: Integration of Peripheral Signals|
|742.15. The Michael J. Fox Foundation’s efforts to understand the relationship between GBA1 and alpha-synuclein through the development and characterization of preclinical models||B. CASEY, N. POLINSKI, T. N. MARTINEZ, S. W. CLARK, S. M. SMITH, R. C. SWITZER III, S. O. AHMAD, S. RAMBOZ, M. SASNER, M. T. HERBERTH, L. MENALLED, M. A. BAPTISTA, K. D. DAVE, M. FRASIER||Poster: 742 - Alpha-Synuclein Models and Mechanisms II|