Human cancers and dog cancers have a surprising amount in common. At The Jackson Laboratory, we believe that by studying canine cancers, we can gain important insights that may benefit both species!
The Jackson Laboratory's Tallwood Canine Cancer Research Initiative (TCCRI) will create a biobank of dog tumors to provide researchers around the world with new information that could lead to treatments, and even potential cures for cancers in humans, and dogs too. Owners of dogs diagnosed with cancer can opt to have their veterinarian remove their dog's tumor during treatment and donate it to the program.
Using comparative genomics, we will use the tumors to identify which parts of DNA could contribute to an increased risk of specific types of cancer in certain dogs. Then we will look for corresponding regions in people to gain insights into new mechanisms that cause similar cancers in humans. This strategy is particularly useful for cancers that are rare among humans, but more commonly found in certain dog breeds such as osteosarcoma.
Our goal is to use the insights we learn about the mechanism of canine cancer to help develop future treatments for humans and dogs.