Welcome from JAX

Edison LiuThank you for your interest in The Jackson Laboratory (JAX) – and welcome!

I’ve shared with you the story of Caroline, a seven-year-old girl with a rare neurological disorder that prevents her from standing, walking, fully using her hands, or breathing comfortably. Caroline’s family has turned to JAX for help.

As a nonprofit biomedical research institute focused on genetics and genomics research to prevent or cure disease, JAX is exploring the genetic mechanisms behind the many different diseases that can affect all of us. This includes cancer, Alzheimer’s and diabetes—diseases that affect millions of people—and rare disorders like Caroline’s.

I welcome you to explore our areas of research relating to these diseases, below.


Edison T. Liu, M.D.
President and CEO, The Jackson Laboratory

It's time to accelerate medical progress.

Since its inception, The Jackson Laboratory has led the discovery of causes, treatments and cures for some of humankind's most devastating genetic diseases. Today, we are speeding the path of discovery from the laboratory bench to clinical care. We are combining the skills and knowledge of our scientists with our institutional strengths in disease modeling and bioinformatics, connecting genetics to genomics, and using our unparalleled knowledge of mouse models of disease to understand the human condition.

JAX research programs are leading efforts to improve human health worldwide.


Addiction is a chronic illness, with genetic, environmental and social aspects. JAX researchers are at the forefront of understanding the genetic factors involved in individuals’ vulnerability to addiction.


JAX researchers are using genomic technologies and specialized mouse models to decipher the changes that occur as a consequence of aging in order to extend our health span, delay age-related health issues, repair damaged organs and improve our quality of life.

Alzheimer's And Other Dementias

Using genomic technologies and specialized mouse models to develop preventative therapies, JAX scientists aim to stop Alzheimer’s before it starts.


Driven by the desire to eradicate cancer, we are leading the future of cancer treatments by combining computational expertise with our unparalleled knowledge of mouse genetics.


JAX researchers investigate the processes that lead to failure to produce insulin in type 1 diabetes and loss of insulin production in type 2 diabetes.


JAX researchers are exploring the effect on health and disease of the microorganisms that outnumber human cells 10 to 1.

Rare Diseases

About 80 percent of rare diseases are genetic in origin, about half affect children, many are fatal, and very few have cures.