When good bacteria go bad

Disruptions of the human microbiome — the trillions of generally harmless bacteria, fungi, and viruses that inhabit our bodies — have been linked to autoimmune diseases, skin and inflammatory disorders, and obesity.

We now know that microbes are essential to our health — the skin microbiome, for example, is protective and resilient — but what specific role do our body’s microbes play in disease? What makes them change over time and sometimes turn against us?

Help forge the next frontier in medicine

Help JAX uncover the potential of the microbiome to deliver treatments for infectious and other diseases.

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Altering our body’s microbiome to promote health

It’s a tantalizing new approach to health: marshaling the powers of our own microbes to build our body’s defenses and fundamentally change how our diseases are treated.

JAX scientists are leading the field of microbial genomics to reveal the biology of the microbiome to develop new therapies and promote health. On the horizon: new insights into skin disorders, Alzheimer’s, cancer, behavior disorders, addiction and athletic performance.


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The Helix Fund fuels our scientific research and education. Learn more about the Helix Fund Signature Societies, named after distinguished JAX scientists, and the Catalyst Circle, JAX’s monthly giving society.
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You can commemorate a special occasion and honor someone special by making a gift to JAX in their name.  Learn more

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Make a planned gift

You can make a lasting gift through your will or give appreciated stocks, bonds, mutual funds, real estate or other tax beneficial assets. Learn more or contact Laura Eldridge, Director of Major and Planned Gifts.


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You can give our scientists needed resources, including endowed chairs, postdoctoral fellowships, and educational opportunities.  Learn more


Learn about microbiome research at JAX

You can help JAX probe the human microbiome for its potential to deliver treatments for infectious and other diseases. Learn more

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Partner With Us: Corporations and Foundations

Contact Peter Lamothe to learn more about opportunities for you to join with JAX to discover treatments and cures.